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Page 1
Genomic analysis of Plasmodium vivax describes patterns of connectivity and putative drivers of adaptation in Ethiopia.
Kebede AM, Sutanto E, Trimarsanto H, Benavente ED, Barnes M, Pearson RD, Siegel SV, Erko B, Assefa A, Getachew S, Aseffa A, Petros B, Lo E, Mohammed R, Yilma D, Rumaseb A, Nosten F, Noviyanti R, Rayner JC, Kwiatkowski DP, Price RN, Golassa L, Auburn S. Kebede AM, et al. Among authors: pearson rd. Sci Rep. 2023 Nov 27;13(1):20788. doi: 10.1038/s41598-023-47889-w. Sci Rep. 2023. PMID: 38012191 Free PMC article.
Drug resistance and vaccine target surveillance of Plasmodium falciparum using nanopore sequencing in Ghana.
Girgis ST, Adika E, Nenyewodey FE, Senoo Jnr DK, Ngoi JM, Bandoh K, Lorenz O, van de Steeg G, Harrott AJR, Nsoh S, Judge K, Pearson RD, Almagro-Garcia J, Saiid S, Atampah S, Amoako EK, Morang'a CM, Asoala V, Adjei ES, Burden W, Roberts-Sengier W, Drury E, Pierce ML, Gonçalves S, Awandare GA, Kwiatkowski DP, Amenga-Etego LN, Hamilton WL. Girgis ST, et al. Among authors: pearson rd. Nat Microbiol. 2023 Dec;8(12):2365-2377. doi: 10.1038/s41564-023-01516-6. Epub 2023 Nov 23. Nat Microbiol. 2023. PMID: 37996707 Free PMC article.
Genomics of Plasmodium vivax in Colombia reveals evidence of local bottle-necking and inter-country connectivity in the Americas.
Sutanto E, Pava Z, Echeverry DF, Lopera-Mesa TM, Montenegro LM, Yasnot-Acosta MF, Benavente ED, Pearson RD, Herrera S, Arévalo-Herrera M, Trimarsanto H, Rumaseb A, Noviyanti R, Kwiatkowski DP, Price RN, Auburn S. Sutanto E, et al. Among authors: pearson rd. Sci Rep. 2023 Nov 13;13(1):19779. doi: 10.1038/s41598-023-46076-1. Sci Rep. 2023. PMID: 37957271 Free PMC article.
Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum.
Kümpornsin K, Kochakarn T, Yeo T, Okombo J, Luth MR, Hoshizaki J, Rawat M, Pearson RD, Schindler KA, Mok S, Park H, Uhlemann AC, Jana GP, Maity BC, Laleu B, Chenu E, Duffy J, Moliner Cubel S, Franco V, Gomez-Lorenzo MG, Gamo FJ, Winzeler EA, Fidock DA, Chookajorn T, Lee MCS. Kümpornsin K, et al. Among authors: pearson rd. Nat Commun. 2023 May 27;14(1):3059. doi: 10.1038/s41467-023-38774-1. Nat Commun. 2023. PMID: 37244916 Free PMC article.
Chloroquine resistance evolution in Plasmodium falciparum is mediated by the putative amino acid transporter AAT1.
Amambua-Ngwa A, Button-Simons KA, Li X, Kumar S, Brenneman KV, Ferrari M, Checkley LA, Haile MT, Shoue DA, McDew-White M, Tindall SM, Reyes A, Delgado E, Dalhoff H, Larbalestier JK, Amato R, Pearson RD, Taylor AB, Nosten FH, D'Alessandro U, Kwiatkowski D, Cheeseman IH, Kappe SHI, Avery SV, Conway DJ, Vaughan AM, Ferdig MT, Anderson TJC. Amambua-Ngwa A, et al. Among authors: pearson rd. Nat Microbiol. 2023 Jul;8(7):1213-1226. doi: 10.1038/s41564-023-01377-z. Epub 2023 May 11. Nat Microbiol. 2023. PMID: 37169919 Free PMC article.
T-cell activation, senescence, and exhaustion in asymptomatic HIV/Leishmania infantum co-infection.
de Oliveira Mendes-Aguiar C, do Monte Alves M, de Albuquerque Lopes Machado A, de Góis Monteiro GR, Medeiros IM, Queiroz JW, Lima ID, Pearson RD, Wilson ME, Glesby MJ, do Nascimento ELT, Jerônimo SMB. de Oliveira Mendes-Aguiar C, et al. Among authors: pearson rd. medRxiv [Preprint]. 2023 Mar 6:2023.03.06.23286828. doi: 10.1101/2023.03.06.23286828. medRxiv. 2023. PMID: 36945413 Free PMC article. Preprint.
A molecular barcode and web-based data analysis tool to identify imported Plasmodium vivax malaria.
Trimarsanto H, Amato R, Pearson RD, Sutanto E, Noviyanti R, Trianty L, Marfurt J, Pava Z, Echeverry DF, Lopera-Mesa TM, Montenegro LM, Tobón-Castaño A, Grigg MJ, Barber B, William T, Anstey NM, Getachew S, Petros B, Aseffa A, Assefa A, Rahim AG, Chau NH, Hien TT, Alam MS, Khan WA, Ley B, Thriemer K, Wangchuck S, Hamedi Y, Adam I, Liu Y, Gao Q, Sriprawat K, Ferreira MU, Laman M, Barry A, Mueller I, Lacerda MVG, Llanos-Cuentas A, Krudsood S, Lon C, Mohammed R, Yilma D, Pereira DB, Espino FEJ, Chu CS, Vélez ID, Namaik-Larp C, Villegas MF, Green JA, Koh G, Rayner JC, Drury E, Gonçalves S, Simpson V, Miotto O, Miles A, White NJ, Nosten F, Kwiatkowski DP, Price RN, Auburn S. Trimarsanto H, et al. Among authors: pearson rd. Commun Biol. 2022 Dec 23;5(1):1411. doi: 10.1038/s42003-022-04352-2. Commun Biol. 2022. PMID: 36564617 Free PMC article.
Malaria outbreak in Laos driven by a selective sweep for Plasmodium falciparum kelch13 R539T mutants: a genetic epidemiology analysis.
Wasakul V, Disratthakit A, Mayxay M, Chindavongsa K, Sengsavath V, Thuy-Nhien N, Pearson RD, Phalivong S, Xayvanghang S, Maude RJ, Gonçalves S, Day NP, Newton PN, Ashley EA, Kwiatkowski DP, Dondorp AM, Miotto O. Wasakul V, et al. Among authors: pearson rd. Lancet Infect Dis. 2023 May;23(5):568-577. doi: 10.1016/S1473-3099(22)00697-1. Epub 2022 Nov 30. Lancet Infect Dis. 2023. PMID: 36462526 Free PMC article.
Geographical distribution and genetic diversity of Plasmodium vivax reticulocyte binding protein 1a correlates with patient antigenicity.
Park JH, Kim MH, Sutanto E, Na SW, Kim MJ, Yeom JS, Nyunt MH, Abbas Elfaki MM, Abdel Hamid MM, Cha SH, Alemu SG, Sriprawat K, Anstey NM, Grigg MJ, Barber BE, William T, Gao Q, Liu Y, Pearson RD, Price RN, Nosten F, Yoon SI, No JH, Han ET, Auburn S, Russell B, Han JH. Park JH, et al. Among authors: pearson rd. PLoS Negl Trop Dis. 2022 Jun 23;16(6):e0010492. doi: 10.1371/journal.pntd.0010492. eCollection 2022 Jun. PLoS Negl Trop Dis. 2022. PMID: 35737709 Free PMC article.
An open dataset of Plasmodium vivax genome variation in 1,895 worldwide samples.
MalariaGEN; Adam I, Alam MS, Alemu S, Amaratunga C, Amato R, Andrianaranjaka V, Anstey NM, Aseffa A, Ashley E, Assefa A, Auburn S, Barber BE, Barry A, Batista Pereira D, Cao J, Chau NH, Chotivanich K, Chu C, Dondorp AM, Drury E, Echeverry DF, Erko B, Espino F, Fairhurst R, Faiz A, Fernanda Villegas M, Gao Q, Golassa L, Goncalves S, Grigg MJ, Hamedi Y, Hien TT, Htut Y, Johnson KJ, Karunaweera N, Khan W, Krudsood S, Kwiatkowski DP, Lacerda M, Ley B, Lim P, Liu Y, Llanos-Cuentas A, Lon C, Lopera-Mesa T, Marfurt J, Michon P, Miotto O, Mohammed R, Mueller I, Namaik-Larp C, Newton PN, Nguyen TN, Nosten F, Noviyanti R, Pava Z, Pearson RD, Petros B, Phyo AP, Price RN, Pukrittayakamee S, Rahim AG, Randrianarivelojosia M, Rayner JC, Rumaseb A, Siegel SV, Simpson VJ, Thriemer K, Tobon-Castano A, Trimarsanto H, Urbano Ferreira M, Vélez ID, Wangchuk S, Wellems TE, White NJ, William T, Yasnot MF, Yilma D. MalariaGEN, et al. Among authors: pearson rd. Wellcome Open Res. 2022 Apr 14;7:136. doi: 10.12688/wellcomeopenres.17795.1. eCollection 2022. Wellcome Open Res. 2022. PMID: 35651694 Free PMC article.
261 results