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Biochemical and proteomics approaches to characterize topoisomerase IIalpha cysteines and DNA as targets responsible for cisplatin-induced inhibition of topoisomerase IIalpha.
Hasinoff BB, Wu X, Krokhin OV, Ens W, Standing KG, Nitiss JL, Sivaram T, Giorgianni A, Yang S, Jiang Y, Yalowich JC. Hasinoff BB, et al. Among authors: nitiss jl. Mol Pharmacol. 2005 Mar;67(3):937-47. doi: 10.1124/mol.104.004416. Epub 2004 Dec 15. Mol Pharmacol. 2005. PMID: 15602006
Chemical reactivity and microbicidal action of bethoxazin.
Chee GL, Bhattarai B, Daniel Gietz R, Alrushaid S, Nitiss JL, Hasinoff BB. Chee GL, et al. Among authors: nitiss jl. Bioorg Med Chem. 2012 Feb 15;20(4):1494-501. doi: 10.1016/j.bmc.2011.12.051. Epub 2012 Jan 5. Bioorg Med Chem. 2012. PMID: 22264763
Topoisomerase assays.
Nitiss JL, Soans E, Rogojina A, Seth A, Mishina M. Nitiss JL, et al. Curr Protoc Pharmacol. 2012 Jun;Chapter 3:Unit 3.3.. doi: 10.1002/0471141755.ph0303s57. Curr Protoc Pharmacol. 2012. PMID: 22684721 Free PMC article.
TDP1 promotes assembly of non-homologous end joining protein complexes on DNA.
Heo J, Li J, Summerlin M, Hays A, Katyal S, McKinnon PJ, Nitiss KC, Nitiss JL, Hanakahi LA. Heo J, et al. Among authors: nitiss kc, nitiss jl. DNA Repair (Amst). 2015 Jun;30:28-37. doi: 10.1016/j.dnarep.2015.03.003. Epub 2015 Mar 17. DNA Repair (Amst). 2015. PMID: 25841101 Free PMC article.
102 results