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Enrichment of HP1a on Drosophila chromosome 4 genes creates an alternate chromatin structure critical for regulation in this heterochromatic domain.
Riddle NC, Jung YL, Gu T, Alekseyenko AA, Asker D, Gui H, Kharchenko PV, Minoda A, Plachetka A, Schwartz YB, Tolstorukov MY, Kuroda MI, Pirrotta V, Karpen GH, Park PJ, Elgin SC. Riddle NC, et al. Among authors: kharchenko pv. PLoS Genet. 2012 Sep;8(9):e1002954. doi: 10.1371/journal.pgen.1002954. Epub 2012 Sep 20. PLoS Genet. 2012. PMID: 23028361 Free PMC article.
Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses.
Hirz T, Mei S, Sarkar H, Kfoury Y, Wu S, Verhoeven BM, Subtelny AO, Zlatev DV, Wszolek MW, Salari K, Murray E, Chen F, Macosko EZ, Wu CL, Scadden DT, Dahl DM, Baryawno N, Saylor PJ, Kharchenko PV, Sykes DB. Hirz T, et al. Among authors: kharchenko pv. Nat Commun. 2023 Feb 7;14(1):663. doi: 10.1038/s41467-023-36325-2. Nat Commun. 2023. PMID: 36750562 Free PMC article.
An atlas of healthy and injured cell states and niches in the human kidney.
Lake BB, Menon R, Winfree S, Hu Q, Melo Ferreira R, Kalhor K, Barwinska D, Otto EA, Ferkowicz M, Diep D, Plongthongkum N, Knoten A, Urata S, Mariani LH, Naik AS, Eddy S, Zhang B, Wu Y, Salamon D, Williams JC, Wang X, Balderrama KS, Hoover PJ, Murray E, Marshall JL, Noel T, Vijayan A, Hartman A, Chen F, Waikar SS, Rosas SE, Wilson FP, Palevsky PM, Kiryluk K, Sedor JR, Toto RD, Parikh CR, Kim EH, Satija R, Greka A, Macosko EZ, Kharchenko PV, Gaut JP, Hodgin JB; KPMP Consortium; Eadon MT, Dagher PC, El-Achkar TM, Zhang K, Kretzler M, Jain S. Lake BB, et al. Among authors: kharchenko pv. Nature. 2023 Jul;619(7970):585-594. doi: 10.1038/s41586-023-05769-3. Epub 2023 Jul 19. Nature. 2023. PMID: 37468583 Free PMC article.
Gene panel selection for targeted spatial transcriptomics.
Zhang Y, Petukhov V, Biederstedt E, Que R, Zhang K, Kharchenko PV. Zhang Y, et al. Among authors: kharchenko pv. Genome Biol. 2024 Jan 25;25(1):35. doi: 10.1186/s13059-024-03174-1. Genome Biol. 2024. PMID: 38273415 Free PMC article.
Nucleosome positioning in human HOX gene clusters.
Kharchenko PV, Woo CJ, Tolstorukov MY, Kingston RE, Park PJ. Kharchenko PV, et al. Genome Res. 2008 Oct;18(10):1554-61. doi: 10.1101/gr.075952.107. Epub 2008 Aug 22. Genome Res. 2008. PMID: 18723689 Free PMC article.
116 results