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Resistance to antidepressant treatment is associated with polymorphisms in the leptin gene, decreased leptin mRNA expression, and decreased leptin serum levels.
Kloiber S, Ripke S, Kohli MA, Reppermund S, Salyakina D, Uher R, McGuffin P, Perlis RH, Hamilton SP, Pütz B, Hennings J, Brückl T, Klengel T, Bettecken T, Ising M, Uhr M, Dose T, Unschuld PG, Zihl J, Binder E, Müller-Myhsok B, Holsboer F, Lucae S. Kloiber S, et al. Among authors: hennings j. Eur Neuropsychopharmacol. 2013 Jul;23(7):653-62. doi: 10.1016/j.euroneuro.2012.08.010. Epub 2012 Sep 29. Eur Neuropsychopharmacol. 2013. PMID: 23026132 Free PMC article.
Clinical characteristics and treatment outcome in a representative sample of depressed inpatients - findings from the Munich Antidepressant Response Signature (MARS) project.
Hennings JM, Owashi T, Binder EB, Horstmann S, Menke A, Kloiber S, Dose T, Wollweber B, Spieler D, Messer T, Lutz R, Künzel H, Bierner T, Pollmächer T, Pfister H, Nickel T, Sonntag A, Uhr M, Ising M, Holsboer F, Lucae S. Hennings JM, et al. J Psychiatr Res. 2009 Jan;43(3):215-29. doi: 10.1016/j.jpsychires.2008.05.002. Epub 2008 Jun 30. J Psychiatr Res. 2009. PMID: 18586274 Clinical Trial.
Suppressive effect of mirtazapine on the HPA system in acutely depressed women seems to be transient and not related to antidepressant action.
Horstmann S, Dose T, Lucae S, Kloiber S, Menke A, Hennings J, Spieler D, Uhr M, Holsboer F, Ising M. Horstmann S, et al. Among authors: hennings j. Psychoneuroendocrinology. 2009 Feb;34(2):238-248. doi: 10.1016/j.psyneuen.2008.09.004. Epub 2008 Oct 15. Psychoneuroendocrinology. 2009. PMID: 18926641 Clinical Trial.
A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression.
Ising M, Lucae S, Binder EB, Bettecken T, Uhr M, Ripke S, Kohli MA, Hennings JM, Horstmann S, Kloiber S, Menke A, Bondy B, Rupprecht R, Domschke K, Baune BT, Arolt V, Rush AJ, Holsboer F, Müller-Myhsok B. Ising M, et al. Arch Gen Psychiatry. 2009 Sep;66(9):966-975. doi: 10.1001/archgenpsychiatry.2009.95. Arch Gen Psychiatry. 2009. PMID: 19736353 Free PMC article.
Association of genetic variants in the neurotrophic receptor-encoding gene NTRK2 and a lifetime history of suicide attempts in depressed patients.
Kohli MA, Salyakina D, Pfennig A, Lucae S, Horstmann S, Menke A, Kloiber S, Hennings J, Bradley BB, Ressler KJ, Uhr M, Müller-Myhsok B, Holsboer F, Binder EB. Kohli MA, et al. Among authors: hennings j. Arch Gen Psychiatry. 2010 Apr;67(4):348-59. doi: 10.1001/archgenpsychiatry.2009.201. Epub 2010 Feb 1. Arch Gen Psychiatry. 2010. PMID: 20124106 Free PMC article.
The neuronal transporter gene SLC6A15 confers risk to major depression.
Kohli MA, Lucae S, Saemann PG, Schmidt MV, Demirkan A, Hek K, Czamara D, Alexander M, Salyakina D, Ripke S, Hoehn D, Specht M, Menke A, Hennings J, Heck A, Wolf C, Ising M, Schreiber S, Czisch M, Müller MB, Uhr M, Bettecken T, Becker A, Schramm J, Rietschel M, Maier W, Bradley B, Ressler KJ, Nöthen MM, Cichon S, Craig IW, Breen G, Lewis CM, Hofman A, Tiemeier H, van Duijn CM, Holsboer F, Müller-Myhsok B, Binder EB. Kohli MA, et al. Among authors: hennings j. Neuron. 2011 Apr 28;70(2):252-65. doi: 10.1016/j.neuron.2011.04.005. Neuron. 2011. PMID: 21521612 Free PMC article.
112 results