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Regulation of cyclic adenosine monophosphate release by selective β2-adrenergic receptor stimulation in human terminal failing myocardium before and after ventricular assist device support.
Kassner A, Toischer K, Bohms B, Kolkhof P, Abraham G, Hasenfuβ G, Morshuis M, Schulte Eistrup S, El-Banayosy A, Gummert J, Milting H. Kassner A, et al. Among authors: toischer k. J Heart Lung Transplant. 2012 Oct;31(10):1127-35. doi: 10.1016/j.healun.2012.07.005. J Heart Lung Transplant. 2012. PMID: 22975104
Relevance of brain natriuretic peptide in preload-dependent regulation of cardiac sarcoplasmic reticulum Ca2+ ATPase expression.
Kögler H, Schott P, Toischer K, Milting H, Van PN, Kohlhaas M, Grebe C, Kassner A, Domeier E, Teucher N, Seidler T, Knöll R, Maier LS, El-Banayosy A, Körfer R, Hasenfuss G. Kögler H, et al. Among authors: toischer k. Circulation. 2006 Jun 13;113(23):2724-32. doi: 10.1161/CIRCULATIONAHA.105.608828. Epub 2006 Jun 5. Circulation. 2006. PMID: 16754798
The contractile adaption to preload depends on the amount of afterload.
Schotola H, Sossalla ST, Renner A, Gummert J, Danner BC, Schott P, Toischer K. Schotola H, et al. Among authors: toischer k. ESC Heart Fail. 2017 Nov;4(4):468-478. doi: 10.1002/ehf2.12164. Epub 2017 Apr 19. ESC Heart Fail. 2017. PMID: 29154423 Free PMC article.
Ca2+/calmodulin-dependent protein kinase II and protein kinase A differentially regulate sarcoplasmic reticulum Ca2+ leak in human cardiac pathology.
Fischer TH, Herting J, Tirilomis T, Renner A, Neef S, Toischer K, Ellenberger D, Förster A, Schmitto JD, Gummert J, Schöndube FA, Hasenfuss G, Maier LS, Sossalla S. Fischer TH, et al. Among authors: toischer k. Circulation. 2013 Aug 27;128(9):970-81. doi: 10.1161/CIRCULATIONAHA.113.001746. Epub 2013 Jul 19. Circulation. 2013. PMID: 23877259
Detrimental proarrhythmogenic interaction of Ca2+/calmodulin-dependent protein kinase II and NaV1.8 in heart failure.
Bengel P, Dybkova N, Tirilomis P, Ahmad S, Hartmann N, A Mohamed B, Krekeler MC, Maurer W, Pabel S, Trum M, Mustroph J, Gummert J, Milting H, Wagner S, Ljubojevic-Holzer S, Toischer K, Maier LS, Hasenfuss G, Streckfuss-Bömeke K, Sossalla S. Bengel P, et al. Among authors: toischer k. Nat Commun. 2021 Nov 15;12(1):6586. doi: 10.1038/s41467-021-26690-1. Nat Commun. 2021. PMID: 34782600 Free PMC article.
Iron-regulatory proteins secure iron availability in cardiomyocytes to prevent heart failure.
Haddad S, Wang Y, Galy B, Korf-Klingebiel M, Hirsch V, Baru AM, Rostami F, Reboll MR, Heineke J, Flögel U, Groos S, Renner A, Toischer K, Zimmermann F, Engeli S, Jordan J, Bauersachs J, Hentze MW, Wollert KC, Kempf T. Haddad S, et al. Among authors: toischer k. Eur Heart J. 2017 Feb 1;38(5):362-372. doi: 10.1093/eurheartj/ehw333. Eur Heart J. 2017. PMID: 27545647
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