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Examination of Org 26576, an AMPA receptor positive allosteric modulator, in patients diagnosed with major depressive disorder: an exploratory, randomized, double-blind, placebo-controlled trial.
Nations KR, Dogterom P, Bursi R, Schipper J, Greenwald S, Zraket D, Gertsik L, Johnstone J, Lee A, Pande Y, Ruigt G, Ereshefsky L. Nations KR, et al. Among authors: dogterom p. J Psychopharmacol. 2012 Dec;26(12):1525-39. doi: 10.1177/0269881112458728. Epub 2012 Sep 6. J Psychopharmacol. 2012. PMID: 22954616 Clinical Trial.
Maximum tolerated dose evaluation of the AMPA modulator Org 26576 in healthy volunteers and depressed patients: a summary and method analysis of bridging research in support of phase II dose selection.
Nations KR, Bursi R, Dogterom P, Ereshefsky L, Gertsik L, Mant T, Schipper J. Nations KR, et al. Among authors: dogterom p. Drugs R D. 2012 Sep 1;12(3):127-39. doi: 10.2165/11634360-000000000-00000. Drugs R D. 2012. PMID: 22852579 Free PMC article. Clinical Trial.
A Phase 1 First-in-Human Single-Ascending-Dose Trial With ESB1609, a Selective Agonist to the Sphingosine-1-Phosphate Receptor 5.
France NP, Rubino C, Safir MC, Maurer M, Duong T, Singamsetty D, Abd-Elaziz K, Chou T, Sankaranarayanan S, Ettema M, Cosford R, Dogterom P, Liu E, Barlow C. France NP, et al. Among authors: dogterom p. Clin Pharmacol Drug Dev. 2023 Jun;12(6):625-638. doi: 10.1002/cpdd.1256. Epub 2023 May 16. Clin Pharmacol Drug Dev. 2023. PMID: 37191222 Clinical Trial.
Safety, Tolerability, Pharmacokinetics and Initial Pharmacodynamics of a Subcommissural Organ-Spondin-Derived Peptide: A Randomized, Placebo-Controlled, Double-Blind, Single Ascending Dose First-in-Human Study.
Bourdès V, Dogterom P, Aleman A, Parmantier P, Colas D, Lemarchant S, Marie S, Chou T, Abd-Elaziz K, Godfrin Y. Bourdès V, et al. Among authors: dogterom p. Neurol Ther. 2022 Sep;11(3):1353-1374. doi: 10.1007/s40120-022-00380-6. Epub 2022 Jul 2. Neurol Ther. 2022. PMID: 35779189 Free PMC article.
Safety and Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT017, an Antiplatelet GPVI (Glycoprotein VI) Fab.
Voors-Pette C, Lebozec K, Dogterom P, Jullien L, Billiald P, Ferlan P, Renaud L, Favre-Bulle O, Avenard G, Machacek M, Plétan Y, Jandrot-Perrus M. Voors-Pette C, et al. Among authors: dogterom p. Arterioscler Thromb Vasc Biol. 2019 May;39(5):956-964. doi: 10.1161/ATVBAHA.118.312314. Arterioscler Thromb Vasc Biol. 2019. PMID: 31017822 Free article. Clinical Trial.
36 results