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A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK.
Campbell JD, McDonough JE, Zeskind JE, Hackett TL, Pechkovsky DV, Brandsma CA, Suzuki M, Gosselink JV, Liu G, Alekseyev YO, Xiao J, Zhang X, Hayashi S, Cooper JD, Timens W, Postma DS, Knight DA, Lenburg ME, Hogg JC, Spira A. Campbell JD, et al. Among authors: postma ds. Genome Med. 2012 Aug 31;4(8):67. doi: 10.1186/gm367. eCollection 2012. Genome Med. 2012. PMID: 22937864 Free PMC article.
A chronic obstructive pulmonary disease related signature in squamous cell lung cancer.
Boelens MC, Gustafson AM, Postma DS, Kok K, van der Vries G, van der Vlies P, Spira A, Lenburg ME, Geerlings M, Sietsma H, Timens W, van den Berg A, Groen HJ. Boelens MC, et al. Among authors: postma ds. Lung Cancer. 2011 May;72(2):177-83. doi: 10.1016/j.lungcan.2010.08.014. Epub 2010 Sep 15. Lung Cancer. 2011. PMID: 20832896
A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairment.
Steiling K, van den Berge M, Hijazi K, Florido R, Campbell J, Liu G, Xiao J, Zhang X, Duclos G, Drizik E, Si H, Perdomo C, Dumont C, Coxson HO, Alekseyev YO, Sin D, Pare P, Hogg JC, McWilliams A, Hiemstra PS, Sterk PJ, Timens W, Chang JT, Sebastiani P, O'Connor GT, Bild AH, Postma DS, Lam S, Spira A, Lenburg ME. Steiling K, et al. Among authors: postma ds. Am J Respir Crit Care Med. 2013 May 1;187(9):933-42. doi: 10.1164/rccm.201208-1449OC. Am J Respir Crit Care Med. 2013. PMID: 23471465 Free PMC article.
Airway gene expression in COPD is dynamic with inhaled corticosteroid treatment and reflects biological pathways associated with disease activity.
van den Berge M, Steiling K, Timens W, Hiemstra PS, Sterk PJ, Heijink IH, Liu G, Alekseyev YO, Lenburg ME, Spira A, Postma DS. van den Berge M, et al. Among authors: postma ds. Thorax. 2014 Jan;69(1):14-23. doi: 10.1136/thoraxjnl-2012-202878. Epub 2013 Aug 7. Thorax. 2014. PMID: 23925644 Free PMC article. Clinical Trial.
Genetic regulation of gene expression in the lung identifies CST3 and CD22 as potential causal genes for airflow obstruction.
Lamontagne M, Timens W, Hao K, Bossé Y, Laviolette M, Steiling K, Campbell JD, Couture C, Conti M, Sherwood K, Hogg JC, Brandsma CA, van den Berge M, Sandford A, Lam S, Lenburg ME, Spira A, Paré PD, Nickle D, Sin DD, Postma DS. Lamontagne M, et al. Among authors: postma ds. Thorax. 2014 Nov;69(11):997-1004. doi: 10.1136/thoraxjnl-2014-205630. Epub 2014 Sep 2. Thorax. 2014. PMID: 25182044
Lung tissue gene-expression signature for the ageing lung in COPD.
de Vries M, Faiz A, Woldhuis RR, Postma DS, de Jong TV, Sin DD, Bossé Y, Nickle DC, Guryev V, Timens W, van den Berge M, Brandsma CA. de Vries M, et al. Among authors: postma ds. Thorax. 2017 Dec 6:thoraxjnl-2017-210074. doi: 10.1136/thoraxjnl-2017-210074. Online ahead of print. Thorax. 2017. PMID: 29212667
Effect of long-term corticosteroid treatment on microRNA and gene-expression profiles in COPD.
Faiz A, Steiling K, Roffel MP, Postma DS, Spira A, Lenburg ME, Borggrewe M, Eijgenraam TR, Jonker MR, Koppelman GH, Pouwels SD, Liu G, Alekseyev YO, Lam S, Hiemstra PS, Sterk PJ, Timens W, Brandsma CA, Heijink IH, van den Berge M. Faiz A, et al. Among authors: postma ds. Eur Respir J. 2019 Apr 25;53(4):1801202. doi: 10.1183/13993003.01202-2018. Print 2019 Apr. Eur Respir J. 2019. PMID: 30846474 Free article.
897 results