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Structure-anti-leukemic activity relationship study of ortho-dihydroxycoumarins in U-937 cells: key role of the δ-lactone ring in determining differentiation-inducing potency and selective pro-apoptotic action.
Vázquez R, Riveiro ME, Vermeulen M, Alonso E, Mondillo C, Facorro G, Piehl L, Gómez N, Moglioni A, Fernández N, Baldi A, Shayo C, Davio C. Vázquez R, et al. Bioorg Med Chem. 2012 Sep 15;20(18):5537-49. doi: 10.1016/j.bmc.2012.07.043. Epub 2012 Aug 2. Bioorg Med Chem. 2012. PMID: 22925447
Structural insights into hydroxycoumarin-induced apoptosis in U-937 cells.
Riveiro ME, Moglioni A, Vazquez R, Gomez N, Facorro G, Piehl L, de Celis ER, Shayo C, Davio C. Riveiro ME, et al. Among authors: vazquez r. Bioorg Med Chem. 2008 Mar 1;16(5):2665-75. doi: 10.1016/j.bmc.2007.11.038. Epub 2007 Nov 19. Bioorg Med Chem. 2008. PMID: 18060791
Synthesis, structural characterization, and pro-apoptotic activity of 1-indanone thiosemicarbazone platinum(II) and palladium(II) complexes: potential as antileukemic agents.
Gómez N, Santos D, Vázquez R, Suescun L, Mombrú A, Vermeulen M, Finkielsztein L, Shayo C, Moglioni A, Gambino D, Davio C. Gómez N, et al. Among authors: vazquez r. ChemMedChem. 2011 Aug 1;6(8):1485-94. doi: 10.1002/cmdc.201100060. Epub 2011 May 23. ChemMedChem. 2011. PMID: 21608131
Development of potent dual PDK1/AurA kinase inhibitors for cancer therapy: Lead-optimization, structural insights, and ADME-Tox profile.
Sestito S, Bacci A, Chiarugi S, Runfola M, Gado F, Margheritis E, Gul S, Riveiro ME, Vazquez R, Huguet S, Manera C, Rezai K, Garau G, Rapposelli S. Sestito S, et al. Among authors: vazquez r. Eur J Med Chem. 2021 Dec 15;226:113895. doi: 10.1016/j.ejmech.2021.113895. Epub 2021 Oct 5. Eur J Med Chem. 2021. PMID: 34624821
560 results