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Phase I pharmacokinetic and pharmacodynamic study of the pan-PI3K/mTORC vascular targeted pro-drug SF1126 in patients with advanced solid tumours and B-cell malignancies.
Eur J Cancer. 2012 Dec;48(18):3319-27. doi: 10.1016/j.ejca.2012.06.027. Epub 2012 Aug 23.
Eur J Cancer. 2012.
PMID: 22921184
Free PMC article.
Clinical Trial.
Resistance to BET Bromodomain Inhibitors Is Mediated by Kinome Reprogramming in Ovarian Cancer.
Kurimchak AM, Shelton C, Duncan KE, Johnson KJ, Brown J, O'Brien S, Gabbasov R, Fink LS, Li Y, Lounsbury N, Abou-Gharbia M, Childers WE, Connolly DC, Chernoff J, Peterson JR, Duncan JS.
Kurimchak AM, et al.
Cell Rep. 2016 Aug 2;16(5):1273-1286. doi: 10.1016/j.celrep.2016.06.091. Epub 2016 Jul 21.
Cell Rep. 2016.
PMID: 27452461
Free PMC article.
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Intrinsic Resistance to MEK Inhibition through BET Protein-Mediated Kinome Reprogramming in NF1-Deficient Ovarian Cancer.
Kurimchak AM, Shelton C, Herrera-Montávez C, Duncan KE, Chernoff J, Duncan JS.
Kurimchak AM, et al.
Mol Cancer Res. 2019 Aug;17(8):1721-1734. doi: 10.1158/1541-7786.MCR-18-1332. Epub 2019 May 1.
Mol Cancer Res. 2019.
PMID: 31043489
Free PMC article.
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PHY34 inhibits autophagy through V-ATPase V0A2 subunit inhibition and CAS/CSE1L nuclear cargo trafficking in high grade serous ovarian cancer.
Salvi A, Young AN, Huntsman AC, Pergande MR, Korkmaz MA, Rathnayake RA, Mize BK, Kinghorn AD, Zhang X, Ratia K, Schirle M, Thomas JR, Brittain SM, Shelton C, Aldrich LN, Cologna SM, Fuchs JR, Burdette JE.
Salvi A, et al.
Cell Death Dis. 2022 Jan 10;13(1):45. doi: 10.1038/s41419-021-04495-w.
Cell Death Dis. 2022.
PMID: 35013112
Free PMC article.
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SPONTANEOUS PNEUMOTHORAX IN THE NEWBORN FOLLOWING ROUTINE CESAREAN SECTION.
SHELTON CF, MARVIN RC.
SHELTON CF, et al.
J Mich State Med Soc. 1964 Mar;63:207-10.
J Mich State Med Soc. 1964.
PMID: 14132479
No abstract available.
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