Simpson AJ - Search Results

1

Ventilator-associated pneumonia is characterized by excessive release of neutrophil proteases in the lung.

Wilkinson TS, Conway Morris A, Kefala K, O'Kane CM, Moore NR, Booth NA, McAuley DF, Dhaliwal K, Walsh TS, Haslett C, Sallenave JM, Simpson AJ. Wilkinson TS, et al. Among authors: simpson aj. Chest. 2012 Dec;142(6):1425-1432. doi: 10.1378/chest.11-3273. Chest. 2012. PMID: 22911225

2

Elafin (elastase-specific inhibitor) has anti-microbial activity against gram-positive and gram-negative respiratory pathogens.

Simpson AJ, Maxwell AI, Govan JR, Haslett C, Sallenave JM. Simpson AJ, et al. FEBS Lett. 1999 Jun 11;452(3):309-13. doi: 10.1016/s0014-5793(99)00670-5. FEBS Lett. 1999. PMID: 10386612 Free article.

3

Adenoviral augmentation of elafin protects the lung against acute injury mediated by activated neutrophils and bacterial infection.

Simpson AJ, Wallace WA, Marsden ME, Govan JR, Porteous DJ, Haslett C, Sallenave JM. Simpson AJ, et al. J Immunol. 2001 Aug 1;167(3):1778-86. doi: 10.4049/jimmunol.167.3.1778. J Immunol. 2001. PMID: 11466403

4

Regulation of adenovirus-mediated elafin transgene expression by bacterial lipopolysaccharide.

Simpson AJ, Cunningham GA, Porteous DJ, Haslett C, Sallenave JM. Simpson AJ, et al. Hum Gene Ther. 2001 Jul 20;12(11):1395-406. doi: 10.1089/104303401750298553. Hum Gene Ther. 2001. PMID: 11485631

5

Endogenous pulmonary antibiotics.

Gibbons MA, Bowdish DM, Davidson DJ, Sallenave JM, Simpson AJ. Gibbons MA, et al. Among authors: simpson aj. Scott Med J. 2006 May;51(2):37-42. doi: 10.1258/RSMSMJ.51.2.37. Scott Med J. 2006. PMID: 16722137 Review.

6

The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system.

Barlow PG, Li Y, Wilkinson TS, Bowdish DM, Lau YE, Cosseau C, Haslett C, Simpson AJ, Hancock RE, Davidson DJ. Barlow PG, et al. Among authors: simpson aj. J Leukoc Biol. 2006 Sep;80(3):509-20. doi: 10.1189/jlb.1005560. Epub 2006 Jun 22. J Leukoc Biol. 2006. PMID: 16793910 Free PMC article.

7

Galectin-3 reduces the severity of pneumococcal pneumonia by augmenting neutrophil function.

Farnworth SL, Henderson NC, Mackinnon AC, Atkinson KM, Wilkinson T, Dhaliwal K, Hayashi K, Simpson AJ, Rossi AG, Haslett C, Sethi T. Farnworth SL, et al. Among authors: simpson aj. Am J Pathol. 2008 Feb;172(2):395-405. doi: 10.2353/ajpath.2008.070870. Epub 2008 Jan 17. Am J Pathol. 2008. PMID: 18202191 Free PMC article.

8

Reactive oxygen species regulate neutrophil recruitment and survival in pneumococcal pneumonia.

Marriott HM, Jackson LE, Wilkinson TS, Simpson AJ, Mitchell TJ, Buttle DJ, Cross SS, Ince PG, Hellewell PG, Whyte MK, Dockrell DH. Marriott HM, et al. Among authors: simpson aj. Am J Respir Crit Care Med. 2008 Apr 15;177(8):887-95. doi: 10.1164/rccm.200707-990OC. Epub 2008 Jan 17. Am J Respir Crit Care Med. 2008. PMID: 18202350 Free PMC article.

9

Evaluation of the effect of diagnostic methodology on the reported incidence of ventilator-associated pneumonia.

Morris AC, Kefala K, Simpson AJ, Wilkinson TS, Everingham K, Kerslake D, Raby S, Laurenson IF, Swann DG, Walsh TS. Morris AC, et al. Among authors: simpson aj. Thorax. 2009 Jun;64(6):516-22. doi: 10.1136/thx.2008.110239. Epub 2009 Feb 12. Thorax. 2009. PMID: 19213771

10

Trappin-2 promotes early clearance of Pseudomonas aeruginosa through CD14-dependent macrophage activation and neutrophil recruitment.

Wilkinson TS, Dhaliwal K, Hamilton TW, Lipka AF, Farrell L, Davidson DJ, Duffin R, Morris AC, Haslett C, Govan JR, Gregory CD, Sallenave JM, Simpson AJ. Wilkinson TS, et al. Among authors: simpson aj. Am J Pathol. 2009 Apr;174(4):1338-46. doi: 10.2353/ajpath.2009.080746. Epub 2009 Mar 5. Am J Pathol. 2009. PMID: 19264904 Free PMC article.

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