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Podoplanin-rich stromal networks induce dendritic cell motility via activation of the C-type lectin receptor CLEC-2.
Acton SE, Astarita JL, Malhotra D, Lukacs-Kornek V, Franz B, Hess PR, Jakus Z, Kuligowski M, Fletcher AL, Elpek KG, Bellemare-Pelletier A, Sceats L, Reynoso ED, Gonzalez SF, Graham DB, Chang J, Peters A, Woodruff M, Kim YA, Swat W, Morita T, Kuchroo V, Carroll MC, Kahn ML, Wucherpfennig KW, Turley SJ. Acton SE, et al. Among authors: kahn ml. Immunity. 2012 Aug 24;37(2):276-89. doi: 10.1016/j.immuni.2012.05.022. Epub 2012 Aug 9. Immunity. 2012. PMID: 22884313 Free PMC article.
Platelets: covert regulators of lymphatic development.
Bertozzi CC, Hess PR, Kahn ML. Bertozzi CC, et al. Among authors: kahn ml. Arterioscler Thromb Vasc Biol. 2010 Dec;30(12):2368-71. doi: 10.1161/ATVBAHA.110.217281. Epub 2010 Nov 11. Arterioscler Thromb Vasc Biol. 2010. PMID: 21071706 Free PMC article. Review.
Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2.
Herzog BH, Fu J, Wilson SJ, Hess PR, Sen A, McDaniel JM, Pan Y, Sheng M, Yago T, Silasi-Mansat R, McGee S, May F, Nieswandt B, Morris AJ, Lupu F, Coughlin SR, McEver RP, Chen H, Kahn ML, Xia L. Herzog BH, et al. Among authors: kahn ml. Nature. 2013 Oct 3;502(7469):105-9. doi: 10.1038/nature12501. Epub 2013 Sep 1. Nature. 2013. PMID: 23995678 Free PMC article.
Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling.
Bertozzi CC, Schmaier AA, Mericko P, Hess PR, Zou Z, Chen M, Chen CY, Xu B, Lu MM, Zhou D, Sebzda E, Santore MT, Merianos DJ, Stadtfeld M, Flake AW, Graf T, Skoda R, Maltzman JS, Koretzky GA, Kahn ML. Bertozzi CC, et al. Among authors: kahn ml. Blood. 2010 Jul 29;116(4):661-70. doi: 10.1182/blood-2010-02-270876. Epub 2010 Apr 2. Blood. 2010. PMID: 20363774 Free PMC article.
Lymphatic function is required prenatally for lung inflation at birth.
Jakus Z, Gleghorn JP, Enis DR, Sen A, Chia S, Liu X, Rawnsley DR, Yang Y, Hess PR, Zou Z, Yang J, Guttentag SH, Nelson CM, Kahn ML. Jakus Z, et al. Among authors: kahn ml. J Exp Med. 2014 May 5;211(5):815-26. doi: 10.1084/jem.20132308. Epub 2014 Apr 14. J Exp Med. 2014. PMID: 24733830 Free PMC article.
Lymph flow regulates collecting lymphatic vessel maturation in vivo.
Sweet DT, Jiménez JM, Chang J, Hess PR, Mericko-Ishizuka P, Fu J, Xia L, Davies PF, Kahn ML. Sweet DT, et al. Among authors: kahn ml. J Clin Invest. 2015 Aug 3;125(8):2995-3007. doi: 10.1172/JCI79386. Epub 2015 Jul 27. J Clin Invest. 2015. PMID: 26214523 Free PMC article.
Platelet ITAM signaling is critical for vascular integrity in inflammation.
Boulaftali Y, Hess PR, Getz TM, Cholka A, Stolla M, Mackman N, Owens AP 3rd, Ware J, Kahn ML, Bergmeier W. Boulaftali Y, et al. Among authors: kahn ml. J Clin Invest. 2013 Feb;123(2):908-16. doi: 10.1172/JCI65154. Epub 2013 Jan 25. J Clin Invest. 2013. PMID: 23348738 Free PMC article.
250 results