Heise CC - Search Results

1

Single-agent lenalidomide in relapsed/refractory mantle cell lymphoma: results from a UK phase II study suggest activity and possible gender differences.

Eve HE, Carey S, Richardson SJ, Heise CC, Mamidipudi V, Shi T, Radford JA, Auer RL, Bullard SH, Rule SA. Eve HE, et al. Among authors: heise cc. Br J Haematol. 2012 Oct;159(2):154-63. doi: 10.1111/bjh.12008. Epub 2012 Aug 9. Br J Haematol. 2012. PMID: 22881386 Free article. Clinical Trial.

2

The class-I HDAC inhibitor MGCD0103 induces apoptosis in Hodgkin lymphoma cell lines and synergizes with proteasome inhibitors by an HDAC6-independent mechanism.

Buglio D, Mamidipudi V, Khaskhely NM, Brady H, Heise C, Besterman J, Martell RE, MacBeth K, Younes A. Buglio D, et al. Br J Haematol. 2010 Nov;151(4):387-96. doi: 10.1111/j.1365-2141.2010.08342.x. Epub 2010 Sep 29. Br J Haematol. 2010. PMID: 20880107 Free PMC article.

3

Lenalidomide efficacy in activated B-cell-like subtype diffuse large B-cell lymphoma is dependent upon IRF4 and cereblon expression.

Zhang LH, Kosek J, Wang M, Heise C, Schafer PH, Chopra R. Zhang LH, et al. Br J Haematol. 2013 Feb;160(4):487-502. doi: 10.1111/bjh.12172. Epub 2012 Dec 18. Br J Haematol. 2013. PMID: 23252516 Free article.

4

Increased cellular accumulation and distribution of amrubicin contribute to its activity in anthracycline-resistant cancer cells.

Mamidipudi V, Shi T, Brady H, Surapaneni S, Chopra R, Aukerman SL, Heise C, Sung V. Mamidipudi V, et al. Cancer Chemother Pharmacol. 2012 Apr;69(4):965-76. doi: 10.1007/s00280-011-1782-x. Epub 2011 Nov 26. Cancer Chemother Pharmacol. 2012. PMID: 22120960

5

Histone deacetylase inhibitor MGCD0103 synergizes with gemcitabine in human pancreatic cells.

Sung V, Richard N, Brady H, Maier A, Kelter G, Heise C. Sung V, et al. Cancer Sci. 2011 Jun;102(6):1201-7. doi: 10.1111/j.1349-7006.2011.01921.x. Epub 2011 Apr 18. Cancer Sci. 2011. PMID: 21375679 Free article.

6

A comparison of azacitidine and decitabine activities in acute myeloid leukemia cell lines.

Hollenbach PW, Nguyen AN, Brady H, Williams M, Ning Y, Richard N, Krushel L, Aukerman SL, Heise C, MacBeth KJ. Hollenbach PW, et al. PLoS One. 2010 Feb 2;5(2):e9001. doi: 10.1371/journal.pone.0009001. PLoS One. 2010. PMID: 20126405 Free PMC article.

7

Azacitidine and decitabine have different mechanisms of action in non-small cell lung cancer cell lines.

Nguyen AN, Hollenbach PW, Richard N, Luna-Moran A, Brady H, Heise C, MacBeth KJ. Nguyen AN, et al. Lung Cancer (Auckl). 2010 Sep 9;1:119-140. doi: 10.2147/LCTT.S11726. eCollection 2010. Lung Cancer (Auckl). 2010. PMID: 28210112 Free PMC article.

8

The class I HDAC inhibitor Romidepsin targets inflammatory breast cancer tumor emboli and synergizes with paclitaxel to inhibit metastasis.

Robertson FM, Chu K, Boley KM, Ye Z, Liu H, Wright MC, Moraes R, Zhang X, Green TL, Barsky SH, Heise C, Cristofanilli M. Robertson FM, et al. J Exp Ther Oncol. 2013;10(3):219-33. J Exp Ther Oncol. 2013. PMID: 24416998

9

Discovery of bicyclic pyrazoles as class III histone deacetylase SIRT1 and SIRT2 inhibitors.

Therrien E, Larouche G, Nguyen N, Rahil J, Lemieux AM, Li Z, Fournel M, Yan TP, Landry AJ, Lefebvre S, Wang JJ, MacBeth K, Heise C, Nguyen A, Besterman JM, Déziel R, Wahhab A. Therrien E, et al. Bioorg Med Chem Lett. 2015 Jun 15;25(12):2514-8. doi: 10.1016/j.bmcl.2015.04.068. Epub 2015 Apr 28. Bioorg Med Chem Lett. 2015. PMID: 25971769

10

Pleiotropic mechanisms of action of lenalidomide efficacy in del(5q) myelodysplastic syndromes.

Heise C, Carter T, Schafer P, Chopra R. Heise C, et al. Expert Rev Anticancer Ther. 2010 Oct;10(10):1663-72. doi: 10.1586/era.10.135. Expert Rev Anticancer Ther. 2010. PMID: 20942636 Review.

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