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RNA splicing is a key mediator of tumour cell plasticity and a therapeutic vulnerability in colorectal cancer.
Hall AE, Pohl SÖ, Cammareri P, Aitken S, Younger NT, Raponi M, Billard CV, Carrancio AB, Bastem A, Freile P, Haward F, Adams IR, Caceres JF, Preyzner P, von Kriegsheim A, Dunlop MG, Din FV, Myant KB. Hall AE, et al. Among authors: freile p. Nat Commun. 2022 May 19;13(1):2791. doi: 10.1038/s41467-022-30489-z. Nat Commun. 2022. PMID: 35589755 Free PMC article.
RAC1B modulates intestinal tumourigenesis via modulation of WNT and EGFR signalling pathways.
Gudiño V, Pohl SÖ, Billard CV, Cammareri P, Bolado A, Aitken S, Stevenson D, Hall AE, Agostino M, Cassidy J, Nixon C, von Kriegsheim A, Freile P, Popplewell L, Dickson G, Murphy L, Wheeler A, Dunlop M, Din F, Strathdee D, Sansom OJ, Myant KB. Gudiño V, et al. Among authors: freile p. Nat Commun. 2021 Apr 20;12(1):2335. doi: 10.1038/s41467-021-22531-3. Nat Commun. 2021. PMID: 33879799 Free PMC article.
Gene Co-Expression Network Analysis Identifies Vitamin D-Associated Gene Modules in Adult Normal Rectal Epithelium Following Supplementation.
Blackmur JP, Vaughan-Shaw PG, Donnelly K, Harris BT, Svinti V, Ochocka-Fox AM, Freile P, Walker M, Gurran T, Reid S, Semple CA, Din FVN, Timofeeva M, Dunlop MG, Farrington SM. Blackmur JP, et al. Among authors: freile p. Front Genet. 2022 Jan 4;12:783970. doi: 10.3389/fgene.2021.783970. eCollection 2021. Front Genet. 2022. PMID: 35096006 Free PMC article.