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Inhibition of DNA topoisomerase I activity and induction of apoptosis by thiazacridine derivatives.
Barros FW, Bezerra DP, Ferreira PM, Cavalcanti BC, Silva TG, Pitta MG, de Lima Mdo C, Galdino SL, Pitta Ida R, Costa-Lotufo LV, Moraes MO, Burbano RR, Guecheva TN, Henriques JA, Pessoa C. Barros FW, et al. Toxicol Appl Pharmacol. 2013 Apr 1;268(1):37-46. doi: 10.1016/j.taap.2013.01.010. Epub 2013 Jan 21. Toxicol Appl Pharmacol. 2013. PMID: 23347980 Free article.
Biological activity of neosergeolide and isobrucein B (and two semi-synthetic derivatives) isolated from the Amazonian medicinal plant Picrolemma sprucei (Simaroubaceae).
Silva EC, Cavalcanti BC, Amorim RC, Lucena JF, Quadros DS, Tadei WP, Montenegro RC, Costa-Lotufo LV, Pessoa C, Moraes MO, Nunomura RC, Nunomura SM, Melo MR, Andrade-Neto VF, Silva LF, Vieira PP, Pohlit AM. Silva EC, et al. Mem Inst Oswaldo Cruz. 2009 Feb;104(1):48-56. doi: 10.1590/s0074-02762009000100008. Mem Inst Oswaldo Cruz. 2009. PMID: 19274376 Free article.
Synthesis and cytotoxic activity of alpha-santonin derivatives.
Arantes FF, Barbosa LC, Alvarenga ES, Demuner AJ, Bezerra DP, Ferreira JR, Costa-Lotufo LV, Pessoa C, Moraes MO. Arantes FF, et al. Eur J Med Chem. 2009 Sep;44(9):3739-45. doi: 10.1016/j.ejmech.2009.03.036. Epub 2009 Apr 5. Eur J Med Chem. 2009. PMID: 19406535
In vitro and in vivo antitumor effects of (4-methoxyphenyl)(3,4,5-trimethoxyphenyl)methanone.
Magalhães HI, Bezerra DP, Cavalcanti BC, Wilke DV, Rotta R, de Lima DP, Beatriz A, Alves AP, Bitencourt Fda S, de Figueiredo IS, Alencar NM, Costa-Lotufo LV, Moraes MO, Pessoa C. Magalhães HI, et al. Cancer Chemother Pharmacol. 2011 Jul;68(1):45-52. doi: 10.1007/s00280-010-1446-2. Epub 2010 Sep 7. Cancer Chemother Pharmacol. 2011. PMID: 20821328
225 results