Baumann K - Search Results

1

Discovery of γ-secretase modulators with a novel activity profile by text-based virtual screening.

Zettl H, Ness J, Hähnke V, Beher D, Jumpertz T, Saric A, Baumann K, Pietrzik CU, Bulic B, Schneider G, Weggen S. Zettl H, et al. Among authors: baumann k. ACS Chem Biol. 2012 Sep 21;7(9):1488-95. doi: 10.1021/cb3001952. Epub 2012 Jul 2. ACS Chem Biol. 2012. PMID: 22725102

2

Independent generation of Abeta42 and Abeta38 peptide species by gamma-secretase.

Czirr E, Cottrell BA, Leuchtenberger S, Kukar T, Ladd TB, Esselmann H, Paul S, Schubenel R, Torpey JW, Pietrzik CU, Golde TE, Wiltfang J, Baumann K, Koo EH, Weggen S. Czirr E, et al. Among authors: baumann k. J Biol Chem. 2008 Jun 20;283(25):17049-54. doi: 10.1074/jbc.M802912200. Epub 2008 Apr 21. J Biol Chem. 2008. PMID: 18426795 Free article.

3

Design, synthesis, and biological evaluation of a novel class of gamma-secretase modulators with PPARgamma activity.

Hieke M, Ness J, Steri R, Dittrich M, Greiner C, Werz O, Baumann K, Schubert-Zsilavecz M, Weggen S, Zettl H. Hieke M, et al. Among authors: baumann k. J Med Chem. 2010 Jun 24;53(12):4691-700. doi: 10.1021/jm1003073. J Med Chem. 2010. PMID: 20503989

4

Insensitivity to Abeta42-lowering nonsteroidal anti-inflammatory drugs and gamma-secretase inhibitors is common among aggressive presenilin-1 mutations.

Czirr E, Leuchtenberger S, Dorner-Ciossek C, Schneider A, Jucker M, Koo EH, Pietrzik CU, Baumann K, Weggen S. Czirr E, et al. Among authors: baumann k. J Biol Chem. 2007 Aug 24;282(34):24504-13. doi: 10.1074/jbc.M700618200. Epub 2007 Jun 15. J Biol Chem. 2007. PMID: 17573346 Free article.

5

Curcumin-derived pyrazoles and isoxazoles: Swiss army knives or blunt tools for Alzheimer's disease?

Narlawar R, Pickhardt M, Leuchtenberger S, Baumann K, Krause S, Dyrks T, Weggen S, Mandelkow E, Schmidt B. Narlawar R, et al. Among authors: baumann k. ChemMedChem. 2008 Jan;3(1):165-72. doi: 10.1002/cmdc.200700218. ChemMedChem. 2008. PMID: 17943713

6

Novel γ-secretase enzyme modulators directly target presenilin protein.

Ebke A, Luebbers T, Fukumori A, Shirotani K, Haass C, Baumann K, Steiner H. Ebke A, et al. Among authors: baumann k. J Biol Chem. 2011 Oct 28;286(43):37181-6. doi: 10.1074/jbc.C111.276972. Epub 2011 Sep 6. J Biol Chem. 2011. PMID: 21896486 Free PMC article.

7

Aminothiazoles as γ-secretase modulators.

Lübbers T, Flohr A, Jolidon S, David-Pierson P, Jacobsen H, Ozmen L, Baumann K. Lübbers T, et al. Among authors: baumann k. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6554-8. doi: 10.1016/j.bmcl.2011.08.060. Epub 2011 Aug 19. Bioorg Med Chem Lett. 2011. PMID: 21924610

8

N-Substituted carbazolyloxyacetic acids modulate Alzheimer associated gamma-secretase.

Narlawar R, Pérez Revuelta BI, Baumann K, Schubenel R, Haass C, Steiner H, Schmidt B. Narlawar R, et al. Among authors: baumann k. Bioorg Med Chem Lett. 2007 Jan 1;17(1):176-82. doi: 10.1016/j.bmcl.2006.09.061. Epub 2006 Oct 10. Bioorg Med Chem Lett. 2007. PMID: 17035010

9

Scaffold of the cyclooxygenase-2 (COX-2) inhibitor carprofen provides Alzheimer gamma-secretase modulators.

Narlawar R, Pérez Revuelta BI, Haass C, Steiner H, Schmidt B, Baumann K. Narlawar R, et al. Among authors: baumann k. J Med Chem. 2006 Dec 28;49(26):7588-91. doi: 10.1021/jm0610200. J Med Chem. 2006. PMID: 17181139

10

NSAID-derived gamma-secretase modulators. Part III: Membrane anchoring.

Baumann S, Höttecke N, Schubenel R, Baumann K, Schmidt B. Baumann S, et al. Among authors: baumann k. Bioorg Med Chem Lett. 2009 Dec 15;19(24):6986-90. doi: 10.1016/j.bmcl.2009.10.035. Epub 2009 Oct 13. Bioorg Med Chem Lett. 2009. PMID: 19879754

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

806 results

Search Page