Xu ZS - Search Results

1

Does a loss of TDP-43 function cause neurodegeneration?

Xu ZS. Xu ZS. Mol Neurodegener. 2012 Jun 14;7:27. doi: 10.1186/1750-1326-7-27. Mol Neurodegener. 2012. PMID: 22697423 Free PMC article. Review.

2

Widespread aggregation of mutant VAPB associated with ALS does not cause motor neuron degeneration or modulate mutant SOD1 aggregation and toxicity in mice.

Qiu L, Qiao T, Beers M, Tan W, Wang H, Yang B, Xu Z. Qiu L, et al. Mol Neurodegener. 2013 Jan 3;8:1. doi: 10.1186/1750-1326-8-1. Mol Neurodegener. 2013. PMID: 23281774 Free PMC article.

3

Partial loss of TDP-43 function causes phenotypes of amyotrophic lateral sclerosis.

Yang C, Wang H, Qiao T, Yang B, Aliaga L, Qiu L, Tan W, Salameh J, McKenna-Yasek DM, Smith T, Peng L, Moore MJ, Brown RH Jr, Cai H, Xu Z. Yang C, et al. Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):E1121-9. doi: 10.1073/pnas.1322641111. Epub 2014 Mar 10. Proc Natl Acad Sci U S A. 2014. PMID: 24616503 Free PMC article.

4

Low-level overexpression of wild type TDP-43 causes late-onset, progressive neurodegeneration and paralysis in mice.

Yang C, Qiao T, Yu J, Wang H, Guo Y, Salameh J, Metterville J, Parsi S, Yusuf I, Brown RH, Cai H, Xu Z. Yang C, et al. PLoS One. 2022 Feb 3;17(2):e0255710. doi: 10.1371/journal.pone.0255710. eCollection 2022. PLoS One. 2022. PMID: 35113871 Free PMC article.

5

Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis.

Wu CH, Fallini C, Ticozzi N, Keagle PJ, Sapp PC, Piotrowska K, Lowe P, Koppers M, McKenna-Yasek D, Baron DM, Kost JE, Gonzalez-Perez P, Fox AD, Adams J, Taroni F, Tiloca C, Leclerc AL, Chafe SC, Mangroo D, Moore MJ, Zitzewitz JA, Xu ZS, van den Berg LH, Glass JD, Siciliano G, Cirulli ET, Goldstein DB, Salachas F, Meininger V, Rossoll W, Ratti A, Gellera C, Bosco DA, Bassell GJ, Silani V, Drory VE, Brown RH Jr, Landers JE. Wu CH, et al. Among authors: xu zs. Nature. 2012 Aug 23;488(7412):499-503. doi: 10.1038/nature11280. Nature. 2012. PMID: 22801503 Free PMC article.

6

Mitochondrial degeneration in amyotrophic lateral sclerosis.

Xu Z, Jung C, Higgins C, Levine J, Kong J. Xu Z, et al. J Bioenerg Biomembr. 2004 Aug;36(4):395-9. doi: 10.1023/B:JOBB.0000041774.12654.e1. J Bioenerg Biomembr. 2004. PMID: 15377878 Review.

7

Inhibition of chaperone activity is a shared property of several Cu,Zn-superoxide dismutase mutants that cause amyotrophic lateral sclerosis.

Tummala H, Jung C, Tiwari A, Higgins CM, Hayward LJ, Xu Z. Tummala H, et al. J Biol Chem. 2005 May 6;280(18):17725-31. doi: 10.1074/jbc.M501705200. Epub 2005 Mar 7. J Biol Chem. 2005. PMID: 15753080 Free article.

8

Widespread spinal cord transduction by intrathecal injection of rAAV delivers efficacious RNAi therapy for amyotrophic lateral sclerosis.

Wang H, Yang B, Qiu L, Yang C, Kramer J, Su Q, Guo Y, Brown RH Jr, Gao G, Xu Z. Wang H, et al. Hum Mol Genet. 2014 Feb 1;23(3):668-81. doi: 10.1093/hmg/ddt454. Epub 2013 Sep 18. Hum Mol Genet. 2014. PMID: 24108104 Free PMC article.

9

Mutant PFN1 causes ALS phenotypes and progressive motor neuron degeneration in mice by a gain of toxicity.

Yang C, Danielson EW, Qiao T, Metterville J, Brown RH Jr, Landers JE, Xu Z. Yang C, et al. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6209-E6218. doi: 10.1073/pnas.1605964113. Epub 2016 Sep 28. Proc Natl Acad Sci U S A. 2016. PMID: 27681617 Free PMC article.

10

Mechanism and treatment of motoneuron degeneration in ALS: what have SOD1 mutants told us?

Xu Z. Xu Z. Amyotroph Lateral Scler Other Motor Neuron Disord. 2000 Sep;1(4):225-34. doi: 10.1080/14660820050515052. Amyotroph Lateral Scler Other Motor Neuron Disord. 2000. PMID: 11465016 Review.

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