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Vascular bioengineering of scaffolds derived from human discarded transplant kidneys using human pluripotent stem cell-derived endothelium.
Leuning DG, Witjas FMR, Maanaoui M, de Graaf AMA, Lievers E, Geuens T, Avramut CM, Wiersma LE, van den Berg CW, Sol WMPJ, de Boer H, Wang G, LaPointe VLS, van der Vlag J, van Kooten C, van den Berg BM, Little MH, Engelse MA, Rabelink TJ. Leuning DG, et al. Among authors: de graaf ama. Am J Transplant. 2019 May;19(5):1328-1343. doi: 10.1111/ajt.15200. Epub 2019 Jan 10. Am J Transplant. 2019. PMID: 30506641 Free PMC article.
A cell-free nutrient-supplemented perfusate allows four-day ex vivo metabolic preservation of human kidneys.
de Haan MJA, Jacobs ME, Witjas FMR, de Graaf AMA, Sánchez-López E, Kostidis S, Giera M, Calderon Novoa F, Chu T, Selzner M, Maanaoui M, de Vries DK, Kers J, Alwayn IPJ, van Kooten C, Heijs B, Wang G, Engelse MA, Rabelink TJ. de Haan MJA, et al. Among authors: de graaf ama. Nat Commun. 2024 May 13;15(1):3818. doi: 10.1038/s41467-024-47106-w. Nat Commun. 2024. PMID: 38740760 Free PMC article.