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Genome-wide analysis of Pax8 binding provides new insights into thyroid functions.
Ruiz-Llorente S, Carrillo Santa de Pau E, Sastre-Perona A, Montero-Conde C, Gómez-López G, Fagin JA, Valencia A, Pisano DG, Santisteban P. Ruiz-Llorente S, et al. Among authors: fagin ja. BMC Genomics. 2012 Apr 24;13:147. doi: 10.1186/1471-2164-13-147. BMC Genomics. 2012. PMID: 22531031 Free PMC article.
Relief of feedback inhibition of HER3 transcription by RAF and MEK inhibitors attenuates their antitumor effects in BRAF-mutant thyroid carcinomas.
Montero-Conde C, Ruiz-Llorente S, Dominguez JM, Knauf JA, Viale A, Sherman EJ, Ryder M, Ghossein RA, Rosen N, Fagin JA. Montero-Conde C, et al. Among authors: fagin ja. Cancer Discov. 2013 May;3(5):520-33. doi: 10.1158/2159-8290.CD-12-0531. Epub 2013 Jan 29. Cancer Discov. 2013. PMID: 23365119 Free PMC article.
Association between BRAF V600E mutation and recurrence of papillary thyroid cancer.
Xing M, Alzahrani AS, Carson KA, Shong YK, Kim TY, Viola D, Elisei R, Bendlová B, Yip L, Mian C, Vianello F, Tuttle RM, Robenshtok E, Fagin JA, Puxeddu E, Fugazzola L, Czarniecka A, Jarzab B, O'Neill CJ, Sywak MS, Lam AK, Riesco-Eizaguirre G, Santisteban P, Nakayama H, Clifton-Bligh R, Tallini G, Holt EH, Sýkorová V. Xing M, et al. Among authors: fagin ja. J Clin Oncol. 2015 Jan 1;33(1):42-50. doi: 10.1200/JCO.2014.56.8253. Epub 2014 Oct 20. J Clin Oncol. 2015. PMID: 25332244 Free PMC article.
Transposon mutagenesis identifies chromatin modifiers cooperating with Ras in thyroid tumorigenesis and detects ATXN7 as a cancer gene.
Montero-Conde C, Leandro-Garcia LJ, Chen X, Oler G, Ruiz-Llorente S, Ryder M, Landa I, Sanchez-Vega F, La K, Ghossein RA, Bajorin DF, Knauf JA, Riordan JD, Dupuy AJ, Fagin JA. Montero-Conde C, et al. Among authors: fagin ja. Proc Natl Acad Sci U S A. 2017 Jun 20;114(25):E4951-E4960. doi: 10.1073/pnas.1702723114. Epub 2017 Jun 5. Proc Natl Acad Sci U S A. 2017. PMID: 28584132 Free PMC article.
Sustained ERK inhibition maximizes responses of BrafV600E thyroid cancers to radioiodine.
Nagarajah J, Le M, Knauf JA, Ferrandino G, Montero-Conde C, Pillarsetty N, Bolaender A, Irwin C, Krishnamoorthy GP, Saqcena M, Larson SM, Ho AL, Seshan V, Ishii N, Carrasco N, Rosen N, Weber WA, Fagin JA. Nagarajah J, et al. Among authors: fagin ja. J Clin Invest. 2016 Nov 1;126(11):4119-4124. doi: 10.1172/JCI89067. Epub 2016 Sep 26. J Clin Invest. 2016. PMID: 27669459 Free PMC article.
Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer.
Xing M, Alzahrani AS, Carson KA, Viola D, Elisei R, Bendlova B, Yip L, Mian C, Vianello F, Tuttle RM, Robenshtok E, Fagin JA, Puxeddu E, Fugazzola L, Czarniecka A, Jarzab B, O'Neill CJ, Sywak MS, Lam AK, Riesco-Eizaguirre G, Santisteban P, Nakayama H, Tufano RP, Pai SI, Zeiger MA, Westra WH, Clark DP, Clifton-Bligh R, Sidransky D, Ladenson PW, Sykorova V. Xing M, et al. Among authors: fagin ja. JAMA. 2013 Apr 10;309(14):1493-501. doi: 10.1001/jama.2013.3190. JAMA. 2013. PMID: 23571588 Free PMC article.
Conditional apoptosis induced by oncogenic ras in thyroid cells.
Shirokawa JM, Elisei R, Knauf JA, Hara T, Wang J, Saavedra HI, Fagin JA. Shirokawa JM, et al. Among authors: fagin ja. Mol Endocrinol. 2000 Nov;14(11):1725-38. doi: 10.1210/mend.14.11.0559. Mol Endocrinol. 2000. PMID: 11075808
253 results