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Discovery of type II inhibitors of TGFβ-activated kinase 1 (TAK1) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2).
Tan L, Nomanbhoy T, Gurbani D, Patricelli M, Hunter J, Geng J, Herhaus L, Zhang J, Pauls E, Ham Y, Choi HG, Xie T, Deng X, Buhrlage SJ, Sim T, Cohen P, Sapkota G, Westover KD, Gray NS. Tan L, et al. Among authors: pauls e. J Med Chem. 2015 Jan 8;58(1):183-96. doi: 10.1021/jm500480k. Epub 2014 Jul 30. J Med Chem. 2015. PMID: 25075558 Free PMC article.
Cell cycle control and HIV-1 susceptibility are linked by CDK6-dependent CDK2 phosphorylation of SAMHD1 in myeloid and lymphoid cells.
Pauls E, Ruiz A, Badia R, Permanyer M, Gubern A, Riveira-Muñoz E, Torres-Torronteras J, Alvarez M, Mothe B, Brander C, Crespo M, Menéndez-Arias L, Clotet B, Keppler OT, Martí R, Posas F, Ballana E, Esté JA. Pauls E, et al. J Immunol. 2014 Aug 15;193(4):1988-97. doi: 10.4049/jimmunol.1400873. Epub 2014 Jul 11. J Immunol. 2014. PMID: 25015816
Induction of interleukins IL-6 and IL-8 by siRNA.
Pauls E, Senserrich J, Bofill M, Clotet B, Esté JA. Pauls E, et al. Clin Exp Immunol. 2007 Jan;147(1):189-96. doi: 10.1111/j.1365-2249.2006.03263.x. Clin Exp Immunol. 2007. PMID: 17177979 Free PMC article.
Inhibition of coreceptor-independent cell-to-cell human immunodeficiency virus type 1 transmission by a CD4-immunoglobulin G2 fusion protein.
Bosch B, Blanco J, Pauls E, Clotet-Codina I, Armand-Ugón M, Grigorov B, Muriaux D, Clotet B, Darlix JL, Esté JA. Bosch B, et al. Among authors: pauls e. Antimicrob Agents Chemother. 2005 Oct;49(10):4296-304. doi: 10.1128/AAC.49.10.4296-4304.2005. Antimicrob Agents Chemother. 2005. PMID: 16189111 Free PMC article.
42 results