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Identification of a series of 1,3,4-oxadiazol-2-amines as potent alpha-7 agonists with efficacy in the novel object recognition model of cognition.
Skidmore J, Atcha Z, Boucherat E, Castelletti L, Chen DW, Coppo FT, Cutler L, Dunsdon RM, Heath BM, Hutchings R, Hurst DN, Javed S, Martin S, Maskell ES, Norton D, Pemberton DJ, Redshaw S, Rutter R, Sehmi SS, Scoccitti T, Temple HE, Theobald P, Ward RW, Wilson DM. Skidmore J, et al. Among authors: rutter r. Bioorg Med Chem Lett. 2012 May 15;22(10):3560-3. doi: 10.1016/j.bmcl.2012.03.040. Epub 2012 Mar 16. Bioorg Med Chem Lett. 2012. PMID: 22503248
The discovery of 2-fluoro-N-(3-fluoro-4-(5-((4-morpholinobutyl)amino)-1,3,4-oxadiazol-2-yl)phenyl)benzamide, a full agonist of the alpha-7 nicotinic acetylcholine receptor showing efficacy in the novel object recognition model of cognition enhancement.
Skidmore J, Atcha Z, Boucherat E, Castelletti L, Chen DW, Coppo FT, Cutler L, Dunsdon RM, Heath BM, Hutchings R, Hurst DN, Javed S, Martin S, Maskell ES, Norton D, Pemberton DJ, Redshaw S, Rutter R, Sehmi SS, Scoccitti T, Temple HE, Theobald P, Ward RW, Wilson DM. Skidmore J, et al. Among authors: rutter r. Bioorg Med Chem Lett. 2012 May 15;22(10):3531-4. doi: 10.1016/j.bmcl.2012.03.062. Epub 2012 Mar 21. Bioorg Med Chem Lett. 2012. PMID: 22503453
Discovery of GSK1997132B a novel centrally penetrant benzimidazole PPARγ partial agonist.
Sime M, Allan AC, Chapman P, Fieldhouse C, Giblin GM, Healy MP, Lambert MH, Leesnitzer LM, Lewis A, Merrihew RV, Rutter RA, Sasse R, Shearer BG, Willson TM, Xu RX, Virley DJ. Sime M, et al. Among authors: rutter ra. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5568-72. doi: 10.1016/j.bmcl.2011.06.088. Epub 2011 Jun 29. Bioorg Med Chem Lett. 2011. PMID: 21798739
Climate-associated variation in the drivers of benthic macroinvertebrate species-area relationships across shallow freshwater lakes.
He H, Li Y, Peng K, Zhang Y, Rutter RP, Jyväsjärvi J, Hämäläinen H, Kelly D, Chase JM, Ntislidou C, Loskutova O, Alcocer J, Jovem-Azevêdo D, Molozzi J, Wang J, Zhang M, Li K, Liu Z, Johansson LS, Søndergaard M, Cai Y, Wang H, Jeppesen E. He H, et al. Among authors: rutter rp. J Anim Ecol. 2024 Jan;93(1):57-70. doi: 10.1111/1365-2656.14028. Epub 2023 Nov 17. J Anim Ecol. 2024. PMID: 37975479
Comparison of cryopreservation methods on T-cell responses to islet and control antigens from type 1 diabetic patients and controls.
Brooks-Worrell B, Tree T, Mannering SI, Durinovic-Bello I, James E, Gottlieb P, Wong S, Zhou Z, Yang L, Cilio CM, Reichow J, Menart B, Rutter R, Schreiner R, Pham M, Petrich de Marquesini L, Lou O, Scotto M, Mallone R, Schloot NC; T-Cell Workshop Committee, Immunology of Diabetes Society. Brooks-Worrell B, et al. Among authors: rutter r. Diabetes Metab Res Rev. 2011 Nov;27(8):737-45. doi: 10.1002/dmrr.1245. Diabetes Metab Res Rev. 2011. PMID: 22069253
33 results