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Pattern of ubiquilin pathology in ALS and FTLD indicates presence of C9ORF72 hexanucleotide expansion.
Brettschneider J, Van Deerlin VM, Robinson JL, Kwong L, Lee EB, Ali YO, Safren N, Monteiro MJ, Toledo JB, Elman L, McCluskey L, Irwin DJ, Grossman M, Molina-Porcel L, Lee VM, Trojanowski JQ. Brettschneider J, et al. Among authors: mccluskey l. Acta Neuropathol. 2012 Jun;123(6):825-39. doi: 10.1007/s00401-012-0970-z. Epub 2012 Mar 18. Acta Neuropathol. 2012. PMID: 22426854 Free PMC article.
Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Igaz LM, Kwong LK, Xu Y, Truax AC, Uryu K, Neumann M, Clark CM, Elman LB, Miller BL, Grossman M, McCluskey LF, Trojanowski JQ, Lee VM. Igaz LM, et al. Among authors: mccluskey lf. Am J Pathol. 2008 Jul;173(1):182-94. doi: 10.2353/ajpath.2008.080003. Epub 2008 Jun 5. Am J Pathol. 2008. PMID: 18535185 Free PMC article.
Cognitive decline and reduced survival in C9orf72 expansion frontotemporal degeneration and amyotrophic lateral sclerosis.
Irwin DJ, McMillan CT, Brettschneider J, Libon DJ, Powers J, Rascovsky K, Toledo JB, Boller A, Bekisz J, Chandrasekaran K, Wood EM, Shaw LM, Woo JH, Cook PA, Wolk DA, Arnold SE, Van Deerlin VM, McCluskey LF, Elman L, Lee VM, Trojanowski JQ, Grossman M. Irwin DJ, et al. Among authors: mccluskey lf. J Neurol Neurosurg Psychiatry. 2013 Feb;84(2):163-9. doi: 10.1136/jnnp-2012-303507. Epub 2012 Oct 31. J Neurol Neurosurg Psychiatry. 2013. PMID: 23117491 Free PMC article.
Topography of FUS pathology distinguishes late-onset BIBD from aFTLD-U.
Lee EB, Russ J, Jung H, Elman LB, Chahine LM, Kremens D, Miller BL, Branch Coslett H, Trojanowski JQ, Van Deerlin VM, McCluskey LF. Lee EB, et al. Among authors: mccluskey lf. Acta Neuropathol Commun. 2013 May 9;1(9):1-11. doi: 10.1186/2051-5960-1-9. Acta Neuropathol Commun. 2013. PMID: 24027631 Free PMC article.
Semi-automated quantification of C9orf72 expansion size reveals inverse correlation between hexanucleotide repeat number and disease duration in frontotemporal degeneration.
Suh E, Lee EB, Neal D, Wood EM, Toledo JB, Rennert L, Irwin DJ, McMillan CT, Krock B, Elman LB, McCluskey LF, Grossman M, Xie SX, Trojanowski JQ, Van Deerlin VM. Suh E, et al. Among authors: mccluskey lf. Acta Neuropathol. 2015 Sep;130(3):363-72. doi: 10.1007/s00401-015-1445-9. Epub 2015 May 29. Acta Neuropathol. 2015. PMID: 26022924 Free PMC article.
Biomarker discovery for Alzheimer's disease, frontotemporal lobar degeneration, and Parkinson's disease.
Hu WT, Chen-Plotkin A, Arnold SE, Grossman M, Clark CM, Shaw LM, McCluskey L, Elman L, Karlawish J, Hurtig HI, Siderowf A, Lee VM, Soares H, Trojanowski JQ. Hu WT, et al. Among authors: mccluskey l. Acta Neuropathol. 2010 Sep;120(3):385-99. doi: 10.1007/s00401-010-0723-9. Epub 2010 Jul 22. Acta Neuropathol. 2010. PMID: 20652578 Free PMC article. Review.
186 results