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RAF265 inhibits the growth of advanced human melanoma tumors.
Su Y, Vilgelm AE, Kelley MC, Hawkins OE, Liu Y, Boyd KL, Kantrow S, Splittgerber RC, Short SP, Sobolik T, Zaja-Milatovic S, Dahlman KB, Amiri KI, Jiang A, Lu P, Shyr Y, Stuart DD, Levy S, Sosman JA, Richmond A. Su Y, et al. Among authors: richmond a. Clin Cancer Res. 2012 Apr 15;18(8):2184-98. doi: 10.1158/1078-0432.CCR-11-1122. Epub 2012 Feb 20. Clin Cancer Res. 2012. PMID: 22351689 Free PMC article.
Elevated constitutive IkappaB kinase activity and IkappaB-alpha phosphorylation in Hs294T melanoma cells lead to increased basal MGSA/GRO-alpha transcription.
Devalaraja MN, Wang DZ, Ballard DW, Richmond A. Devalaraja MN, et al. Among authors: richmond a. Cancer Res. 1999 Mar 15;59(6):1372-7. Cancer Res. 1999. PMID: 10096573
Recently, we demonstrated an increased rate of IkappaB-alpha degradation in Hs294T cells, which leads to an increased nuclear localization of NF-kappaB (R. L. Shattuck-Brandt and A. Richmond. Cancer Res., 57: 3032-3039, 1997). Here we demonstrate that Hs294T melanom …
Recently, we demonstrated an increased rate of IkappaB-alpha degradation in Hs294T cells, which leads to an increased nuclear localization o …
Constitutive IkappaB kinase activity correlates with nuclear factor-kappaB activation in human melanoma cells.
Yang J, Richmond A. Yang J, et al. Among authors: richmond a. Cancer Res. 2001 Jun 15;61(12):4901-9. Cancer Res. 2001. PMID: 11406569
Constitutive IKK activity associated with increased IkappaBalpha phosphorylation and degradation contribute to the high level of endogenous nuclear factor-kappaB (NF-kappaB) activation in Hs294T melanoma cells as compared with RPE cells (R. L. Shattuck-Brandt and A. Ric …
Constitutive IKK activity associated with increased IkappaBalpha phosphorylation and degradation contribute to the high level of endogenous …
480 results