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GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain.
Leurs U, Klein AB, McSpadden ED, Griem-Krey N, Solbak SMØ, Houlton J, Villumsen IS, Vogensen SB, Hamborg L, Gauger SJ, Palmelund LB, Larsen ASG, Shehata MA, Kelstrup CD, Olsen JV, Bach A, Burnie RO, Kerr DS, Gowing EK, Teurlings SMW, Chi CC, Gee CL, Frølund B, Kornum BR, van Woerden GM, Clausen RP, Kuriyan J, Clarkson AN, Wellendorph P. Leurs U, et al. Among authors: solbak smo. Proc Natl Acad Sci U S A. 2021 Aug 3;118(31):e2108079118. doi: 10.1073/pnas.2108079118. Proc Natl Acad Sci U S A. 2021. PMID: 34330837 Free PMC article.
Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds.
Pallesen JS, Narayanan D, Tran KT, Solbak SMØ, Marseglia G, Sørensen LME, Høj LJ, Munafò F, Carmona RMC, Garcia AD, Desu HL, Brambilla R, Johansen TN, Popowicz GM, Sattler M, Gajhede M, Bach A. Pallesen JS, et al. Among authors: solbak smo. J Med Chem. 2021 Apr 22;64(8):4623-4661. doi: 10.1021/acs.jmedchem.0c02094. Epub 2021 Apr 5. J Med Chem. 2021. PMID: 33818106 Free article.
The dynamics of linear polyubiquitin.
Jussupow A, Messias AC, Stehle R, Geerlof A, Solbak SMØ, Paissoni C, Bach A, Sattler M, Camilloni C. Jussupow A, et al. Among authors: solbak smo. Sci Adv. 2020 Oct 14;6(42):eabc3786. doi: 10.1126/sciadv.abc3786. Print 2020 Oct. Sci Adv. 2020. PMID: 33055165 Free PMC article.
21 results