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Page 1
Antitelomerase therapy provokes ALT and mitochondrial adaptive mechanisms in cancer.
Hu J, Hwang SS, Liesa M, Gan B, Sahin E, Jaskelioff M, Ding Z, Ying H, Boutin AT, Zhang H, Johnson S, Ivanova E, Kost-Alimova M, Protopopov A, Wang YA, Shirihai OS, Chin L, DePinho RA. Hu J, et al. Among authors: protopopov a. Cell. 2012 Feb 17;148(4):651-63. doi: 10.1016/j.cell.2011.12.028. Cell. 2012. PMID: 22341440 Free PMC article.
Telomerase reactivation following telomere dysfunction yields murine prostate tumors with bone metastases.
Ding Z, Wu CJ, Jaskelioff M, Ivanova E, Kost-Alimova M, Protopopov A, Chu GC, Wang G, Lu X, Labrot ES, Hu J, Wang W, Xiao Y, Zhang H, Zhang J, Zhang J, Gan B, Perry SR, Jiang S, Li L, Horner JW, Wang YA, Chin L, DePinho RA. Ding Z, et al. Among authors: protopopov a. Cell. 2012 Mar 2;148(5):896-907. doi: 10.1016/j.cell.2012.01.039. Epub 2012 Feb 16. Cell. 2012. PMID: 22341455 Free PMC article.
Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer.
Kapoor A, Yao W, Ying H, Hua S, Liewen A, Wang Q, Zhong Y, Wu CJ, Sadanandam A, Hu B, Chang Q, Chu GC, Al-Khalil R, Jiang S, Xia H, Fletcher-Sananikone E, Lim C, Horwitz GI, Viale A, Pettazzoni P, Sanchez N, Wang H, Protopopov A, Zhang J, Heffernan T, Johnson RL, Chin L, Wang YA, Draetta G, DePinho RA. Kapoor A, et al. Among authors: protopopov a. Cell. 2014 Jul 3;158(1):185-197. doi: 10.1016/j.cell.2014.06.003. Epub 2014 Jun 19. Cell. 2014. PMID: 24954535 Free PMC article.
FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis.
Paik JH, Ding Z, Narurkar R, Ramkissoon S, Muller F, Kamoun WS, Chae SS, Zheng H, Ying H, Mahoney J, Hiller D, Jiang S, Protopopov A, Wong WH, Chin L, Ligon KL, DePinho RA. Paik JH, et al. Among authors: protopopov a. Cell Stem Cell. 2009 Nov 6;5(5):540-53. doi: 10.1016/j.stem.2009.09.013. Cell Stem Cell. 2009. PMID: 19896444 Free PMC article.
Telomere dysfunction induces metabolic and mitochondrial compromise.
Sahin E, Colla S, Liesa M, Moslehi J, Müller FL, Guo M, Cooper M, Kotton D, Fabian AJ, Walkey C, Maser RS, Tonon G, Foerster F, Xiong R, Wang YA, Shukla SA, Jaskelioff M, Martin ES, Heffernan TP, Protopopov A, Ivanova E, Mahoney JE, Kost-Alimova M, Perry SR, Bronson R, Liao R, Mulligan R, Shirihai OS, Chin L, DePinho RA. Sahin E, et al. Among authors: protopopov a. Nature. 2011 Feb 17;470(7334):359-65. doi: 10.1038/nature09787. Epub 2011 Feb 9. Nature. 2011. PMID: 21307849 Free PMC article.
Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice.
Jaskelioff M, Muller FL, Paik JH, Thomas E, Jiang S, Adams AC, Sahin E, Kost-Alimova M, Protopopov A, Cadiñanos J, Horner JW, Maratos-Flier E, Depinho RA. Jaskelioff M, et al. Among authors: protopopov a. Nature. 2011 Jan 6;469(7328):102-6. doi: 10.1038/nature09603. Epub 2010 Nov 28. Nature. 2011. PMID: 21113150 Free PMC article.
Role of telomere dysfunction in cardiac failure in Duchenne muscular dystrophy.
Mourkioti F, Kustan J, Kraft P, Day JW, Zhao MM, Kost-Alimova M, Protopopov A, DePinho RA, Bernstein D, Meeker AK, Blau HM. Mourkioti F, et al. Among authors: protopopov a. Nat Cell Biol. 2013 Aug;15(8):895-904. doi: 10.1038/ncb2790. Epub 2013 Jul 7. Nat Cell Biol. 2013. PMID: 23831727 Free PMC article.
213 results