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Overexpression of IL-11 promotes premalignant gastric epithelial hyperplasia in isolation from germline gp130-JAK-STAT driver mutations.
Buzzelli JN, O'Connor L, Scurr M, Chung Nien Chin S, Catubig A, Ng GZ, Oshima M, Oshima H, Giraud AS, Sutton P, Judd LM, Menheniott TR. Buzzelli JN, et al. Am J Physiol Gastrointest Liver Physiol. 2019 Feb 1;316(2):G251-G262. doi: 10.1152/ajpgi.00304.2018. Epub 2018 Dec 6. Am J Physiol Gastrointest Liver Physiol. 2019. PMID: 30520693 Free article.
Elevated IL-33 expression is associated with pediatric eosinophilic esophagitis, and exogenous IL-33 promotes eosinophilic esophagitis development in mice.
Judd LM, Heine RG, Menheniott TR, Buzzelli J, O'Brien-Simpson N, Pavlic D, O'Connor L, Al Gazali K, Hamilton O, Scurr M, Collison AM, Mattes J, Allen KJ, Giraud AS. Judd LM, et al. Am J Physiol Gastrointest Liver Physiol. 2016 Jan 1;310(1):G13-25. doi: 10.1152/ajpgi.00290.2015. Epub 2015 Oct 29. Am J Physiol Gastrointest Liver Physiol. 2016. PMID: 26514775 Free article.
Coordinate expression loss of GKN1 and GKN2 in gastric cancer via impairment of a glucocorticoid-responsive enhancer.
Chung Nien Chin S, O'Connor L, Scurr M, Busada JT, Graham AN, Alipour Talesh G, Tran CP, Sarkar S, Minamoto T, Giraud AS, Cidlowski JA, Sutton P, Menheniott TR. Chung Nien Chin S, et al. Am J Physiol Gastrointest Liver Physiol. 2020 Aug 1;319(2):G175-G188. doi: 10.1152/ajpgi.00019.2020. Epub 2020 Jun 15. Am J Physiol Gastrointest Liver Physiol. 2020. PMID: 32538140 Free PMC article.
Loss of gastrokine-2 drives premalignant gastric inflammation and tumor progression.
Menheniott TR, O'Connor L, Chionh YT, Däbritz J, Scurr M, Rollo BN, Ng GZ, Jacobs S, Catubig A, Kurklu B, Mercer S, Minamoto T, Ong DE, Ferrero RL, Fox JG, Wang TC, Sutton P, Judd LM, Giraud AS. Menheniott TR, et al. J Clin Invest. 2016 Apr 1;126(4):1383-400. doi: 10.1172/JCI82655. Epub 2016 Mar 14. J Clin Invest. 2016. PMID: 26974160 Free PMC article.
Cre transgene results in global attenuation of the cAMP/PKA pathway.
Gangoda L, Doerflinger M, Lee YY, Rahimi A, Etemadi N, Chau D, Milla L, O'Connor L, Puthalakath H. Gangoda L, et al. Cell Death Dis. 2012 Aug 9;3(8):e365. doi: 10.1038/cddis.2012.110. Cell Death Dis. 2012. PMID: 22875002 Free PMC article.
673 results