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Evidence for a shift to anaerobic metabolism in adipose tissue in efavirenz-containing regimens for HIV with different nucleoside backbones.
McGee KC, Shahmanesh M, Boothby M, Nightingale P, Gathercole LL, Tripathi G, Harte AL, Shojaee-Moradie F, Umpleby AM, Das S, Al-Daghri NM, McTernan PG, Tomlinson JW. McGee KC, et al. Among authors: nightingale p. Antivir Ther. 2012;17(3):495-507. doi: 10.3851/IMP2017. Epub 2011 Dec 13. Antivir Ther. 2012. PMID: 22300946 Clinical Trial.
Antiretroviral treatment reduces very-low-density lipoprotein and intermediate-density lipoprotein apolipoprotein B fractional catabolic rate in human immunodeficiency virus-infected patients with mild dyslipidemia.
Shahmanesh M, Das S, Stolinski M, Shojaee-Moradie F, Jackson NC, Jefferson W, Cramb R, Nightingale P, Umpleby AM. Shahmanesh M, et al. Among authors: nightingale p. J Clin Endocrinol Metab. 2005 Feb;90(2):755-60. doi: 10.1210/jc.2004-1273. Epub 2004 Nov 2. J Clin Endocrinol Metab. 2005. PMID: 15522931
In treatment-naïve and antiretroviral-treated subjects with HIV, reduced plasma adiponectin is associated with a reduced fractional clearance rate of VLDL, IDL and LDL apolipoprotein B-100.
Das S, Shahmanesh M, Stolinski M, Shojaee-Moradie F, Jefferson W, Jackson NC, Cobbold M, Nightingale P, Umpleby AM. Das S, et al. Among authors: nightingale p. Diabetologia. 2006 Mar;49(3):538-42. doi: 10.1007/s00125-005-0085-3. Epub 2006 Jan 24. Diabetologia. 2006. PMID: 16432707
Mitotane therapy in adrenocortical cancer induces CYP3A4 and inhibits 5α-reductase, explaining the need for personalized glucocorticoid and androgen replacement.
Chortis V, Taylor AE, Schneider P, Tomlinson JW, Hughes BA, O'Neil DM, Libé R, Allolio B, Bertagna X, Bertherat J, Beuschlein F, Fassnacht M, Karavitaki N, Mannelli M, Mantero F, Opocher G, Porfiri E, Quinkler M, Sherlock M, Terzolo M, Nightingale P, Shackleton CH, Stewart PM, Hahner S, Arlt W. Chortis V, et al. Among authors: nightingale p. J Clin Endocrinol Metab. 2013 Jan;98(1):161-71. doi: 10.1210/jc.2012-2851. Epub 2012 Nov 16. J Clin Endocrinol Metab. 2013. PMID: 23162091 Free article. Clinical Trial.
Cerebrospinal fluid corticosteroid levels and cortisol metabolism in patients with idiopathic intracranial hypertension: a link between 11beta-HSD1 and intracranial pressure regulation?
Sinclair AJ, Walker EA, Burdon MA, van Beek AP, Kema IP, Hughes BA, Murray PI, Nightingale PG, Stewart PM, Rauz S, Tomlinson JW. Sinclair AJ, et al. Among authors: nightingale pg. J Clin Endocrinol Metab. 2010 Dec;95(12):5348-56. doi: 10.1210/jc.2010-0729. Epub 2010 Sep 8. J Clin Endocrinol Metab. 2010. PMID: 20826586
370 results