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Computational protein design enables a novel one-carbon assimilation pathway.
Siegel JB, Smith AL, Poust S, Wargacki AJ, Bar-Even A, Louw C, Shen BW, Eiben CB, Tran HM, Noor E, Gallaher JL, Bale J, Yoshikuni Y, Gelb MH, Keasling JD, Stoddard BL, Lidstrom ME, Baker D. Siegel JB, et al. Among authors: eiben cb. Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3704-9. doi: 10.1073/pnas.1500545112. Epub 2015 Mar 9. Proc Natl Acad Sci U S A. 2015. PMID: 25775555 Free PMC article.
Improvement of a potential anthrax therapeutic by computational protein design.
Wu SJ, Eiben CB, Carra JH, Huang I, Zong D, Liu P, Wu CT, Nivala J, Dunbar J, Huber T, Senft J, Schokman R, Smith MD, Mills JH, Friedlander AM, Baker D, Siegel JB. Wu SJ, et al. Among authors: eiben cb. J Biol Chem. 2011 Sep 16;286(37):32586-92. doi: 10.1074/jbc.M111.251041. Epub 2011 Jul 18. J Biol Chem. 2011. PMID: 21768086 Free PMC article.
Mevalonate Pathway Promiscuity Enables Noncanonical Terpene Production.
Eiben CB, de Rond T, Bloszies C, Gin J, Chiniquy J, Baidoo EEK, Petzold CJ, Hillson NJ, Fiehn O, Keasling JD. Eiben CB, et al. ACS Synth Biol. 2019 Oct 18;8(10):2238-2247. doi: 10.1021/acssynbio.9b00230. Epub 2019 Oct 2. ACS Synth Biol. 2019. PMID: 31576747
Massively Parallel Fitness Profiling Reveals Multiple Novel Enzymes in Pseudomonas putida Lysine Metabolism.
Thompson MG, Blake-Hedges JM, Cruz-Morales P, Barajas JF, Curran SC, Eiben CB, Harris NC, Benites VT, Gin JW, Sharpless WA, Twigg FF, Skyrud W, Krishna RN, Pereira JH, Baidoo EEK, Petzold CJ, Adams PD, Arkin AP, Deutschbauer AM, Keasling JD. Thompson MG, et al. Among authors: eiben cb. mBio. 2019 May 7;10(3):e02577-18. doi: 10.1128/mBio.02577-18. mBio. 2019. PMID: 31064836 Free PMC article.
Fatty Acid and Alcohol Metabolism in Pseudomonas putida: Functional Analysis Using Random Barcode Transposon Sequencing.
Thompson MG, Incha MR, Pearson AN, Schmidt M, Sharpless WA, Eiben CB, Cruz-Morales P, Blake-Hedges JM, Liu Y, Adams CA, Haushalter RW, Krishna RN, Lichtner P, Blank LM, Mukhopadhyay A, Deutschbauer AM, Shih PM, Keasling JD. Thompson MG, et al. Among authors: eiben cb. Appl Environ Microbiol. 2020 Oct 15;86(21):e01665-20. doi: 10.1128/AEM.01665-20. Print 2020 Oct 15. Appl Environ Microbiol. 2020. PMID: 32826213 Free PMC article.
An iron (II) dependent oxygenase performs the last missing step of plant lysine catabolism.
Thompson MG, Blake-Hedges JM, Pereira JH, Hangasky JA, Belcher MS, Moore WM, Barajas JF, Cruz-Morales P, Washington LJ, Haushalter RW, Eiben CB, Liu Y, Skyrud W, Benites VT, Barnum TP, Baidoo EEK, Scheller HV, Marletta MA, Shih PM, Adams PD, Keasling JD. Thompson MG, et al. Among authors: eiben cb. Nat Commun. 2020 Jun 10;11(1):2931. doi: 10.1038/s41467-020-16815-3. Nat Commun. 2020. PMID: 32523014 Free PMC article.
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