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DNA breaks and chromosome pulverization from errors in mitosis.
Crasta K, Ganem NJ, Dagher R, Lantermann AB, Ivanova EV, Pan Y, Nezi L, Protopopov A, Chowdhury D, Pellman D. Crasta K, et al. Among authors: ganem nj. Nature. 2012 Jan 18;482(7383):53-8. doi: 10.1038/nature10802. Nature. 2012. PMID: 22258507 Free PMC article.
Tetraploidy, aneuploidy and cancer.
Ganem NJ, Storchova Z, Pellman D. Ganem NJ, et al. Curr Opin Genet Dev. 2007 Apr;17(2):157-62. doi: 10.1016/j.gde.2007.02.011. Epub 2007 Feb 26. Curr Opin Genet Dev. 2007. PMID: 17324569 Review.
Limiting the proliferation of polyploid cells.
Ganem NJ, Pellman D. Ganem NJ, et al. Cell. 2007 Nov 2;131(3):437-40. doi: 10.1016/j.cell.2007.10.024. Cell. 2007. PMID: 17981108 Free article. Review.
Whole-genome doubling confers unique genetic vulnerabilities on tumour cells.
Quinton RJ, DiDomizio A, Vittoria MA, Kotýnková K, Ticas CJ, Patel S, Koga Y, Vakhshoorzadeh J, Hermance N, Kuroda TS, Parulekar N, Taylor AM, Manning AL, Campbell JD, Ganem NJ. Quinton RJ, et al. Among authors: ganem nj. Nature. 2021 Feb;590(7846):492-497. doi: 10.1038/s41586-020-03133-3. Epub 2021 Jan 27. Nature. 2021. PMID: 33505027 Free PMC article.
Emi1 maintains genomic integrity during zebrafish embryogenesis and cooperates with p53 in tumor suppression.
Rhodes J, Amsterdam A, Sanda T, Moreau LA, McKenna K, Heinrichs S, Ganem NJ, Ho KW, Neuberg DS, Johnston A, Ahn Y, Kutok JL, Hromas R, Wray J, Lee C, Murphy C, Radtke I, Downing JR, Fleming MD, MacConaill LE, Amatruda JF, Gutierrez A, Galinsky I, Stone RM, Ross EA, Pellman DS, Kanki JP, Look AT. Rhodes J, et al. Among authors: ganem nj. Mol Cell Biol. 2009 Nov;29(21):5911-22. doi: 10.1128/MCB.00558-09. Epub 2009 Aug 24. Mol Cell Biol. 2009. PMID: 19704007 Free PMC article.
Identification of the kinase STK25 as an upstream activator of LATS signaling.
Lim S, Hermance N, Mudianto T, Mustaly HM, Mauricio IPM, Vittoria MA, Quinton RJ, Howell BW, Cornils H, Manning AL, Ganem NJ. Lim S, et al. Among authors: ganem nj. Nat Commun. 2019 Apr 4;10(1):1547. doi: 10.1038/s41467-019-09597-w. Nat Commun. 2019. PMID: 30948712 Free PMC article.
34 results