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Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth.
Chiavarina B, Whitaker-Menezes D, Martinez-Outschoorn UE, Witkiewicz AK, Birbe R, Howell A, Pestell RG, Smith J, Daniel R, Sotgia F, Lisanti MP. Chiavarina B, et al. Among authors: pestell rg. Cancer Biol Ther. 2011 Dec 15;12(12):1101-13. doi: 10.4161/cbt.12.12.18703. Epub 2011 Dec 15. Cancer Biol Ther. 2011. PMID: 22236875 Free PMC article.
p42/44 MAP kinase-dependent and -independent signaling pathways regulate caveolin-1 gene expression. Activation of Ras-MAP kinase and protein kinase a signaling cascades transcriptionally down-regulates caveolin-1 promoter activity.
Engelman JA, Zhang XL, Razani B, Pestell RG, Lisanti MP. Engelman JA, et al. Among authors: pestell rg. J Biol Chem. 1999 Nov 5;274(45):32333-41. doi: 10.1074/jbc.274.45.32333. J Biol Chem. 1999. PMID: 10542274 Free article.
Caveolin-1 inhibits epidermal growth factor-stimulated lamellipod extension and cell migration in metastatic mammary adenocarcinoma cells (MTLn3). Transformation suppressor effects of adenovirus-mediated gene delivery of caveolin-1.
Zhang W, Razani B, Altschuler Y, Bouzahzah B, Mostov KE, Pestell RG, Lisanti MP. Zhang W, et al. Among authors: pestell rg. J Biol Chem. 2000 Jul 7;275(27):20717-25. doi: 10.1074/jbc.M909895199. J Biol Chem. 2000. PMID: 10748172 Free article.
The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways.
D'Amico M, Hulit J, Amanatullah DF, Zafonte BT, Albanese C, Bouzahzah B, Fu M, Augenlicht LH, Donehower LA, Takemaru K, Moon RT, Davis R, Lisanti MP, Shtutman M, Zhurinsky J, Ben-Ze'ev A, Troussard AA, Dedhar S, Pestell RG. D'Amico M, et al. Among authors: pestell rg. J Biol Chem. 2000 Oct 20;275(42):32649-57. doi: 10.1074/jbc.M000643200. J Biol Chem. 2000. PMID: 10915780 Free article.
491 results