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Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling.
Major MB, Camp ND, Berndt JD, Yi X, Goldenberg SJ, Hubbert C, Biechele TL, Gingras AC, Zheng N, Maccoss MJ, Angers S, Moon RT. Major MB, et al. Among authors: moon rt. Science. 2007 May 18;316(5827):1043-6. doi: 10.1126/science/1141515. Science. 2007. PMID: 17510365
Beta-catenin gets jaded and von Hippel-Lindau is to blame.
Berndt JD, Moon RT, Major MB. Berndt JD, et al. Among authors: moon rt. Trends Biochem Sci. 2009 Mar;34(3):101-4. doi: 10.1016/j.tibs.2008.12.002. Epub 2009 Feb 11. Trends Biochem Sci. 2009. PMID: 19217300
Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling.
James RG, Biechele TL, Conrad WH, Camp ND, Fass DM, Major MB, Sommer K, Yi X, Roberts BS, Cleary MA, Arthur WT, MacCoss M, Rawlings DJ, Haggarty SJ, Moon RT. James RG, et al. Among authors: moon rt. Sci Signal. 2009 May 26;2(72):ra25. doi: 10.1126/scisignal.2000230. Sci Signal. 2009. PMID: 19471023 Free PMC article.
WIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signaling.
James RG, Davidson KC, Bosch KA, Biechele TL, Robin NC, Taylor RJ, Major MB, Camp ND, Fowler K, Martins TJ, Moon RT. James RG, et al. Among authors: moon rt. PLoS One. 2012;7(12):e50457. doi: 10.1371/journal.pone.0050457. Epub 2012 Dec 5. PLoS One. 2012. PMID: 23227175 Free PMC article.
287 results