Pons J - Search Results

1

Structural basis of C-terminal β-amyloid peptide binding by the antibody ponezumab for the treatment of Alzheimer's disease.

La Porte SL, Bollini SS, Lanz TA, Abdiche YN, Rusnak AS, Ho WH, Kobayashi D, Harrabi O, Pappas D, Mina EW, Milici AJ, Kawabe TT, Bales K, Lin JC, Pons J. La Porte SL, et al. Among authors: pons j. J Mol Biol. 2012 Aug 24;421(4-5):525-36. doi: 10.1016/j.jmb.2011.11.047. Epub 2011 Dec 13. J Mol Biol. 2012. PMID: 22197375

2

39-week toxicity and toxicokinetic study of ponezumab (PF-04360365) in cynomolgus monkeys with 12-week recovery period.

Freeman GB, Lin JC, Pons J, Raha NM. Freeman GB, et al. Among authors: pons j. J Alzheimers Dis. 2012;28(3):531-41. doi: 10.3233/JAD-2011-110869. J Alzheimers Dis. 2012. PMID: 22045481

3

Generating bispecific human IgG1 and IgG2 antibodies from any antibody pair.

Strop P, Ho WH, Boustany LM, Abdiche YN, Lindquist KC, Farias SE, Rickert M, Appah CT, Pascua E, Radcliffe T, Sutton J, Chaparro-Riggers J, Chen W, Casas MG, Chin SM, Wong OK, Liu SH, Vergara G, Shelton D, Rajpal A, Pons J. Strop P, et al. Among authors: pons j. J Mol Biol. 2012 Jul 13;420(3):204-19. doi: 10.1016/j.jmb.2012.04.020. Epub 2012 Apr 25. J Mol Biol. 2012. PMID: 22543237

4

Determining the binding affinity of therapeutic monoclonal antibodies towards their native unpurified antigens in human serum.

Bee C, Abdiche YN, Pons J, Rajpal A. Bee C, et al. Among authors: pons j. PLoS One. 2013 Nov 6;8(11):e80501. doi: 10.1371/journal.pone.0080501. eCollection 2013. PLoS One. 2013. PMID: 24223227 Free PMC article.

5

Probing the binding mechanism and affinity of tanezumab, a recombinant humanized anti-NGF monoclonal antibody, using a repertoire of biosensors.

Abdiche YN, Malashock DS, Pons J. Abdiche YN, et al. Among authors: pons j. Protein Sci. 2008 Aug;17(8):1326-35. doi: 10.1110/ps.035402.108. Epub 2008 May 27. Protein Sci. 2008. PMID: 18505735 Free PMC article.

6

Proprotein convertase substilisin/kexin type 9 antagonism reduces low-density lipoprotein cholesterol in statin-treated hypercholesterolemic nonhuman primates.

Liang H, Chaparro-Riggers J, Strop P, Geng T, Sutton JE, Tsai D, Bai L, Abdiche Y, Dilley J, Yu J, Wu S, Chin SM, Lee NA, Rossi A, Lin JC, Rajpal A, Pons J, Shelton DL. Liang H, et al. Among authors: pons j. J Pharmacol Exp Ther. 2012 Feb;340(2):228-36. doi: 10.1124/jpet.111.187419. Epub 2011 Oct 21. J Pharmacol Exp Ther. 2012. PMID: 22019884

7

Label-free epitope binning assays of monoclonal antibodies enable the identification of antigen heterogeneity.

Abdiche YN, Lindquist KC, Stone DM, Rajpal A, Pons J. Abdiche YN, et al. Among authors: pons j. J Immunol Methods. 2012 Aug 31;382(1-2):101-16. doi: 10.1016/j.jim.2012.05.010. Epub 2012 May 17. J Immunol Methods. 2012. PMID: 22609372

8

Exploring blocking assays using Octet, ProteOn, and Biacore biosensors.

Abdiche YN, Malashock DS, Pinkerton A, Pons J. Abdiche YN, et al. Among authors: pons j. Anal Biochem. 2009 Mar 15;386(2):172-80. doi: 10.1016/j.ab.2008.11.038. Epub 2008 Dec 7. Anal Biochem. 2009. PMID: 19111520

9

Expanding the ProteOn XPR36 biosensor into a 36-ligand array expedites protein interaction analysis.

Abdiche YN, Lindquist KC, Pinkerton A, Pons J, Rajpal A. Abdiche YN, et al. Among authors: pons j. Anal Biochem. 2011 Apr 1;411(1):139-51. doi: 10.1016/j.ab.2010.12.020. Epub 2010 Dec 17. Anal Biochem. 2011. PMID: 21168382

10

Synthetic antibodies designed on natural sequence landscapes.

Zhai W, Glanville J, Fuhrmann M, Mei L, Ni I, Sundar PD, Van Blarcom T, Abdiche Y, Lindquist K, Strohner R, Telman D, Cappuccilli G, Finlay WJ, Van den Brulle J, Cox DR, Pons J, Rajpal A. Zhai W, et al. Among authors: pons j. J Mol Biol. 2011 Sep 9;412(1):55-71. doi: 10.1016/j.jmb.2011.07.018. Epub 2011 Jul 23. J Mol Biol. 2011. PMID: 21787786

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