Lanz TA - Search Results

1

Structural basis of C-terminal β-amyloid peptide binding by the antibody ponezumab for the treatment of Alzheimer's disease.

La Porte SL, Bollini SS, Lanz TA, Abdiche YN, Rusnak AS, Ho WH, Kobayashi D, Harrabi O, Pappas D, Mina EW, Milici AJ, Kawabe TT, Bales K, Lin JC, Pons J. La Porte SL, et al. Among authors: lanz ta. J Mol Biol. 2012 Aug 24;421(4-5):525-36. doi: 10.1016/j.jmb.2011.11.047. Epub 2011 Dec 13. J Mol Biol. 2012. PMID: 22197375

2

Solid-phase extraction enhances detection of beta-amyloid peptides in plasma and enables Abeta quantification following passive immunization with Abeta antibodies.

Lanz TA, Schachter JB. Lanz TA, et al. J Neurosci Methods. 2008 Mar 30;169(1):16-22. doi: 10.1016/j.jneumeth.2007.11.009. Epub 2007 Nov 22. J Neurosci Methods. 2008. PMID: 18160105

3

Diamide amino-imidazoles: a novel series of γ-secretase inhibitors for the treatment of Alzheimer's disease.

Brodney MA, Auperin DD, Becker SL, Bronk BS, Brown TM, Coffman KJ, Finley JE, Hicks CD, Karmilowicz MJ, Lanz TA, Liston D, Liu X, Martin BA, Nelson RB, Nolan CE, Oborski CE, Parker CP, Richter KE, Pozdnyakov N, Sahagan BG, Schachter JB, Sokolowski SA, Tate B, Van Deusen JW, Wood DE, Wood KM. Brodney MA, et al. Among authors: lanz ta. Bioorg Med Chem Lett. 2011 May 1;21(9):2631-6. doi: 10.1016/j.bmcl.2010.12.117. Epub 2010 Dec 30. Bioorg Med Chem Lett. 2011. PMID: 21269825

4

Lack of specific amyloid-beta(1-42) suppression by nonsteroidal anti-inflammatory drugs in young, plaque-free Tg2576 mice and in guinea pig neuronal cultures.

Lanz TA, Fici GJ, Merchant KM. Lanz TA, et al. J Pharmacol Exp Ther. 2005 Jan;312(1):399-406. doi: 10.1124/jpet.104.073965. Epub 2004 Aug 30. J Pharmacol Exp Ther. 2005. PMID: 15340006

5

Concentration-dependent modulation of amyloid-beta in vivo and in vitro using the gamma-secretase inhibitor, LY-450139.

Lanz TA, Karmilowicz MJ, Wood KM, Pozdnyakov N, Du P, Piotrowski MA, Brown TM, Nolan CE, Richter KE, Finley JE, Fei Q, Ebbinghaus CF, Chen YL, Spracklin DK, Tate B, Geoghegan KF, Lau LF, Auperin DD, Schachter JB. Lanz TA, et al. J Pharmacol Exp Ther. 2006 Nov;319(2):924-33. doi: 10.1124/jpet.106.110700. Epub 2006 Aug 18. J Pharmacol Exp Ther. 2006. PMID: 16920992

6

Demonstration of a common artifact in immunosorbent assays of brain extracts: development of a solid-phase extraction protocol to enable measurement of amyloid-beta from wild-type rodent brain.

Lanz TA, Schachter JB. Lanz TA, et al. J Neurosci Methods. 2006 Oct 15;157(1):71-81. doi: 10.1016/j.jneumeth.2006.03.023. Epub 2006 May 4. J Neurosci Methods. 2006. PMID: 16678274

7

Transcriptomic analysis of genetically defined autism candidate genes reveals common mechanisms of action.

Lanz TA, Guilmette E, Gosink MM, Fischer JE, Fitzgerald LW, Stephenson DT, Pletcher MT. Lanz TA, et al. Mol Autism. 2013 Nov 15;4(1):45. doi: 10.1186/2040-2392-4-45. Mol Autism. 2013. PMID: 24238429 Free PMC article.

8

Peripheral elevation of IGF-1 fails to alter Abeta clearance in multiple in vivo models.

Lanz TA, Salatto CT, Semproni AR, Marconi M, Brown TM, Richter KE, Schmidt K, Nelson FR, Schachter JB. Lanz TA, et al. Biochem Pharmacol. 2008 Mar 1;75(5):1093-103. doi: 10.1016/j.bcp.2007.11.001. Epub 2007 Nov 12. Biochem Pharmacol. 2008. PMID: 18076866

9

Transcriptional Profiling of a Selective CREB Binding Protein Bromodomain Inhibitor Highlights Therapeutic Opportunities.

Chekler EL, Pellegrino JA, Lanz TA, Denny RA, Flick AC, Coe J, Langille J, Basak A, Liu S, Stock IA, Sahasrabudhe P, Bonin PD, Lee K, Pletcher MT, Jones LH. Chekler EL, et al. Among authors: lanz ta. Chem Biol. 2015 Dec 17;22(12):1588-96. doi: 10.1016/j.chembiol.2015.10.013. Epub 2015 Dec 3. Chem Biol. 2015. PMID: 26670081

10

Dendritic spine loss in the hippocampus of young PDAPP and Tg2576 mice and its prevention by the ApoE2 genotype.

Lanz TA, Carter DB, Merchant KM. Lanz TA, et al. Neurobiol Dis. 2003 Aug;13(3):246-53. doi: 10.1016/s0969-9961(03)00079-2. Neurobiol Dis. 2003. PMID: 12901839

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