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A useful approach to identify novel small-molecule inhibitors of Wnt-dependent transcription.
Ewan K, Pajak B, Stubbs M, Todd H, Barbeau O, Quevedo C, Botfield H, Young R, Ruddle R, Samuel L, Battersby A, Raynaud F, Allen N, Wilson S, Latinkic B, Workman P, McDonald E, Blagg J, Aherne W, Dale T. Ewan K, et al. Among authors: quevedo c. Cancer Res. 2010 Jul 15;70(14):5963-73. doi: 10.1158/0008-5472.CAN-10-1028. Epub 2010 Jul 7. Cancer Res. 2010. PMID: 20610623 Free PMC article.
Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds.
Cruz-Migoni A, Canning P, Quevedo CE, Bataille CJR, Bery N, Miller A, Russell AJ, Phillips SEV, Carr SB, Rabbitts TH. Cruz-Migoni A, et al. Among authors: quevedo ce. Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2545-2550. doi: 10.1073/pnas.1811360116. Epub 2019 Jan 25. Proc Natl Acad Sci U S A. 2019. PMID: 30683716 Free PMC article.
A novel color change mechanism for breast cancer biomarker detection: naphthoquinones as specific ligands of human arylamine N-acetyltransferase 1.
Laurieri N, Egleton JE, Varney A, Thinnes CC, Quevedo CE, Seden PT, Thompson S, Rodrigues-Lima F, Dairou J, Dupret JM, Russell AJ, Sim E. Laurieri N, et al. Among authors: quevedo ce. PLoS One. 2013 Aug 5;8(8):e70600. doi: 10.1371/journal.pone.0070600. Print 2013. PLoS One. 2013. PMID: 23940600 Free PMC article.
Thiazolidine derivatives as potent and selective inhibitors of the PIM kinase family.
Bataille CJ, Brennan MB, Byrne S, Davies SG, Durbin M, Fedorov O, Huber KV, Jones AM, Knapp S, Liu G, Nadali A, Quevedo CE, Russell AJ, Walker RG, Westwood R, Wynne GM. Bataille CJ, et al. Bioorg Med Chem. 2017 May 1;25(9):2657-2665. doi: 10.1016/j.bmc.2017.02.056. Epub 2017 Feb 28. Bioorg Med Chem. 2017. PMID: 28341403 Free article.
53 results