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DC-SIGN increases the affinity of HIV-1 envelope glycoprotein interaction with CD4.
Hijazi K, Wang Y, Scala C, Jeffs S, Longstaff C, Stieh D, Haggarty B, Vanham G, Schols D, Balzarini J, Jones IM, Hoxie J, Shattock R, Kelly CG. Hijazi K, et al. Among authors: schols d. PLoS One. 2011;6(12):e28307. doi: 10.1371/journal.pone.0028307. Epub 2011 Dec 7. PLoS One. 2011. PMID: 22163292 Free PMC article.
Combination of antiretroviral drugs as microbicides.
Balzarini J, Schols D. Balzarini J, et al. Among authors: schols d. Curr HIV Res. 2012 Jan 1;10(1):53-60. doi: 10.2174/157016212799304652. Curr HIV Res. 2012. PMID: 22264046
The lantibiotic peptide labyrinthopeptin A1 demonstrates broad anti-HIV and anti-HSV activity with potential for microbicidal applications.
Férir G, Petrova MI, Andrei G, Huskens D, Hoorelbeke B, Snoeck R, Vanderleyden J, Balzarini J, Bartoschek S, Brönstrup M, Süssmuth RD, Schols D. Férir G, et al. Among authors: schols d. PLoS One. 2013 May 28;8(5):e64010. doi: 10.1371/journal.pone.0064010. Print 2013. PLoS One. 2013. PMID: 23724015 Free PMC article.
Actinohivin, a broadly neutralizing prokaryotic lectin, inhibits HIV-1 infection by specifically targeting high-mannose-type glycans on the gp120 envelope.
Hoorelbeke B, Huskens D, Férir G, François KO, Takahashi A, Van Laethem K, Schols D, Tanaka H, Balzarini J. Hoorelbeke B, et al. Among authors: schols d. Antimicrob Agents Chemother. 2010 Aug;54(8):3287-301. doi: 10.1128/AAC.00254-10. Epub 2010 May 24. Antimicrob Agents Chemother. 2010. PMID: 20498311 Free PMC article.
484 results