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LGALS3BP, lectin galactoside-binding soluble 3 binding protein, induces vascular endothelial growth factor in human breast cancer cells and promotes angiogenesis.
Piccolo E, Tinari N, Semeraro D, Traini S, Fichera I, Cumashi A, La Sorda R, Spinella F, Bagnato A, Lattanzio R, D'Egidio M, Di Risio A, Stampolidis P, Piantelli M, Natoli C, Ullrich A, Iacobelli S. Piccolo E, et al. Among authors: fichera i. J Mol Med (Berl). 2013 Jan;91(1):83-94. doi: 10.1007/s00109-012-0936-6. Epub 2012 Aug 5. J Mol Med (Berl). 2013. PMID: 22864925
Adenoviral vaccine targeting multiple neoantigens as strategy to eradicate large tumors combined with checkpoint blockade.
D'Alise AM, Leoni G, Cotugno G, Troise F, Langone F, Fichera I, De Lucia M, Avalle L, Vitale R, Leuzzi A, Bignone V, Di Matteo E, Tucci FG, Poli V, Lahm A, Catanese MT, Folgori A, Colloca S, Nicosia A, Scarselli E. D'Alise AM, et al. Among authors: fichera i. Nat Commun. 2019 Jun 19;10(1):2688. doi: 10.1038/s41467-019-10594-2. Nat Commun. 2019. PMID: 31217437 Free PMC article.
A Genetic Vaccine Encoding Shared Cancer Neoantigens to Treat Tumors with Microsatellite Instability.
Leoni G, D'Alise AM, Cotugno G, Langone F, Garzia I, De Lucia M, Fichera I, Vitale R, Bignone V, Tucci FG, Mori F, Leuzzi A, Di Matteo E, Troise F, Abbate A, Merone R, Ruzza V, Diodoro MG, Yadav M, Gordon-Alonso M, Vanhaver C, Panigada M, Soprana E, Siccardi A, Folgori A, Colloca S, van der Bruggen P, Nicosia A, Lahm A, Catanese MT, Scarselli E. Leoni G, et al. Among authors: fichera i. Cancer Res. 2020 Sep 15;80(18):3972-3982. doi: 10.1158/0008-5472.CAN-20-1072. Epub 2020 Jul 20. Cancer Res. 2020. PMID: 32690723