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A suggested role for mitochondria in Noonan syndrome.
Lee I, Pecinova A, Pecina P, Neel BG, Araki T, Kucherlapati R, Roberts AE, Hüttemann M. Lee I, et al. Among authors: pecina p. Biochim Biophys Acta. 2010 Feb;1802(2):275-83. doi: 10.1016/j.bbadis.2009.10.005. Epub 2009 Oct 14. Biochim Biophys Acta. 2010. PMID: 19835954 Free PMC article.
Cytochrome c oxidase subunit 4 isoform 2-knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology.
Hüttemann M, Lee I, Gao X, Pecina P, Pecinova A, Liu J, Aras S, Sommer N, Sanderson TH, Tost M, Neff F, Aguilar-Pimentel JA, Becker L, Naton B, Rathkolb B, Rozman J, Favor J, Hans W, Prehn C, Puk O, Schrewe A, Sun M, Höfler H, Adamski J, Bekeredjian R, Graw J, Adler T, Busch DH, Klingenspor M, Klopstock T, Ollert M, Wolf E, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Weissmann N, Doan JW, Bassett DJ, Grossman LI. Hüttemann M, et al. Among authors: pecina p. FASEB J. 2012 Sep;26(9):3916-30. doi: 10.1096/fj.11-203273. Epub 2012 Jun 22. FASEB J. 2012. PMID: 22730437 Free PMC article.
Cytochrome C is tyrosine 97 phosphorylated by neuroprotective insulin treatment.
Sanderson TH, Mahapatra G, Pecina P, Ji Q, Yu K, Sinkler C, Varughese A, Kumar R, Bukowski MJ, Tousignant RN, Salomon AR, Lee I, Hüttemann M. Sanderson TH, et al. Among authors: pecina p. PLoS One. 2013 Nov 5;8(11):e78627. doi: 10.1371/journal.pone.0078627. eCollection 2013. PLoS One. 2013. PMID: 24223835 Free PMC article.
48 results