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Page 1
PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling.
Shrestha Y, Schafer EJ, Boehm JS, Thomas SR, He F, Du J, Wang S, Barretina J, Weir BA, Zhao JJ, Polyak K, Golub TR, Beroukhim R, Hahn WC. Shrestha Y, et al. Among authors: polyak k. Oncogene. 2012 Jul 19;31(29):3397-408. doi: 10.1038/onc.2011.515. Epub 2011 Nov 21. Oncogene. 2012. PMID: 22105362 Free PMC article.
Molecular characterization of the tumor microenvironment in breast cancer.
Allinen M, Beroukhim R, Cai L, Brennan C, Lahti-Domenici J, Huang H, Porter D, Hu M, Chin L, Richardson A, Schnitt S, Sellers WR, Polyak K. Allinen M, et al. Among authors: polyak k. Cancer Cell. 2004 Jul;6(1):17-32. doi: 10.1016/j.ccr.2004.06.010. Cancer Cell. 2004. PMID: 15261139 Free article.
HIN-1, an inhibitor of cell growth, invasion, and AKT activation.
Krop I, Parker MT, Bloushtain-Qimron N, Porter D, Gelman R, Sasaki H, Maurer M, Terry MB, Parsons R, Polyak K. Krop I, et al. Among authors: polyak k. Cancer Res. 2005 Nov 1;65(21):9659-69. doi: 10.1158/0008-5472.CAN-05-1663. Cancer Res. 2005. PMID: 16266985
Roots and stems: stem cells in cancer.
Polyak K, Hahn WC. Polyak K, et al. Nat Med. 2006 Mar;12(3):296-300. doi: 10.1038/nm1379. Nat Med. 2006. PMID: 16520777
Molecular definition of breast tumor heterogeneity.
Shipitsin M, Campbell LL, Argani P, Weremowicz S, Bloushtain-Qimron N, Yao J, Nikolskaya T, Serebryiskaya T, Beroukhim R, Hu M, Halushka MK, Sukumar S, Parker LM, Anderson KS, Harris LN, Garber JE, Richardson AL, Schnitt SJ, Nikolsky Y, Gelman RS, Polyak K. Shipitsin M, et al. Among authors: polyak k. Cancer Cell. 2007 Mar;11(3):259-73. doi: 10.1016/j.ccr.2007.01.013. Cancer Cell. 2007. PMID: 17349583 Free article.
Integrative genomic approaches identify IKBKE as a breast cancer oncogene.
Boehm JS, Zhao JJ, Yao J, Kim SY, Firestein R, Dunn IF, Sjostrom SK, Garraway LA, Weremowicz S, Richardson AL, Greulich H, Stewart CJ, Mulvey LA, Shen RR, Ambrogio L, Hirozane-Kishikawa T, Hill DE, Vidal M, Meyerson M, Grenier JK, Hinkle G, Root DE, Roberts TM, Lander ES, Polyak K, Hahn WC. Boehm JS, et al. Among authors: polyak k. Cell. 2007 Jun 15;129(6):1065-79. doi: 10.1016/j.cell.2007.03.052. Cell. 2007. PMID: 17574021 Free article.
Breast cancer: origins and evolution.
Polyak K. Polyak K. J Clin Invest. 2007 Nov;117(11):3155-63. doi: 10.1172/JCI33295. J Clin Invest. 2007. PMID: 17975657 Free PMC article. Review.
Regulation of in situ to invasive breast carcinoma transition.
Hu M, Yao J, Carroll DK, Weremowicz S, Chen H, Carrasco D, Richardson A, Violette S, Nikolskaya T, Nikolsky Y, Bauerlein EL, Hahn WC, Gelman RS, Allred C, Bissell MJ, Schnitt S, Polyak K. Hu M, et al. Among authors: polyak k. Cancer Cell. 2008 May;13(5):394-406. doi: 10.1016/j.ccr.2008.03.007. Cancer Cell. 2008. PMID: 18455123 Free PMC article.
Control of cyclin D1 and breast tumorigenesis by the EglN2 prolyl hydroxylase.
Zhang Q, Gu J, Li L, Liu J, Luo B, Cheung HW, Boehm JS, Ni M, Geisen C, Root DE, Polyak K, Brown M, Richardson AL, Hahn WC, Kaelin WG Jr, Bommi-Reddy A. Zhang Q, et al. Among authors: polyak k. Cancer Cell. 2009 Nov 6;16(5):413-24. doi: 10.1016/j.ccr.2009.09.029. Cancer Cell. 2009. PMID: 19878873 Free PMC article.
251 results