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Gα(q/11) signaling tonically modulates nociceptor function and contributes to activity-dependent sensitization.
Tappe-Theodor A, Constantin CE, Tegeder I, Lechner SG, Langeslag M, Lepcynzsky P, Wirotanseng RI, Kurejova M, Agarwal N, Nagy G, Todd A, Wettschureck N, Offermanns S, Kress M, Lewin GR, Kuner R. Tappe-Theodor A, et al. Among authors: kurejova m. Pain. 2012 Jan;153(1):184-196. doi: 10.1016/j.pain.2011.10.014. Epub 2011 Nov 8. Pain. 2012. PMID: 22071319
A novel biological role for the phospholipid lysophosphatidylinositol in nociceptive sensitization via activation of diverse G-protein signalling pathways in sensory nerves in vivo.
Gangadharan V, Selvaraj D, Kurejova M, Njoo C, Gritsch S, Škoricová D, Horstmann H, Offermanns S, Brown AJ, Kuner T, Tappe-Theodor A, Kuner R. Gangadharan V, et al. Among authors: kurejova m. Pain. 2013 Dec;154(12):2801-2812. doi: 10.1016/j.pain.2013.08.019. Epub 2013 Aug 22. Pain. 2013. PMID: 23973358
Presynaptically localized cyclic GMP-dependent protein kinase 1 is a key determinant of spinal synaptic potentiation and pain hypersensitivity.
Luo C, Gangadharan V, Bali KK, Xie RG, Agarwal N, Kurejova M, Tappe-Theodor A, Tegeder I, Feil S, Lewin G, Polgar E, Todd AJ, Schlossmann J, Hofmann F, Liu DL, Hu SJ, Feil R, Kuner T, Kuner R. Luo C, et al. Among authors: kurejova m. PLoS Biol. 2012;10(3):e1001283. doi: 10.1371/journal.pbio.1001283. Epub 2012 Mar 13. PLoS Biol. 2012. PMID: 22427743 Free PMC article.
A Functional Role for VEGFR1 Expressed in Peripheral Sensory Neurons in Cancer Pain.
Selvaraj D, Gangadharan V, Michalski CW, Kurejova M, Stösser S, Srivastava K, Schweizerhof M, Waltenberger J, Ferrara N, Heppenstall P, Shibuya M, Augustin HG, Kuner R. Selvaraj D, et al. Among authors: kurejova m. Cancer Cell. 2015 Jun 8;27(6):780-96. doi: 10.1016/j.ccell.2015.04.017. Cancer Cell. 2015. PMID: 26058077 Free PMC article.
17 results