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Gα(q/11) signaling tonically modulates nociceptor function and contributes to activity-dependent sensitization.
Tappe-Theodor A, Constantin CE, Tegeder I, Lechner SG, Langeslag M, Lepcynzsky P, Wirotanseng RI, Kurejova M, Agarwal N, Nagy G, Todd A, Wettschureck N, Offermanns S, Kress M, Lewin GR, Kuner R. Tappe-Theodor A, et al. Among authors: agarwal n. Pain. 2012 Jan;153(1):184-196. doi: 10.1016/j.pain.2011.10.014. Epub 2011 Nov 8. Pain. 2012. PMID: 22071319
A molecular basis of analgesic tolerance to cannabinoids.
Tappe-Theodor A, Agarwal N, Katona I, Rubino T, Martini L, Swiercz J, Mackie K, Monyer H, Parolaro D, Whistler J, Kuner T, Kuner R. Tappe-Theodor A, et al. Among authors: agarwal n. J Neurosci. 2007 Apr 11;27(15):4165-77. doi: 10.1523/JNEUROSCI.5648-06.2007. J Neurosci. 2007. PMID: 17428994 Free PMC article.
Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors.
Agarwal N, Pacher P, Tegeder I, Amaya F, Constantin CE, Brenner GJ, Rubino T, Michalski CW, Marsicano G, Monory K, Mackie K, Marian C, Batkai S, Parolaro D, Fischer MJ, Reeh P, Kunos G, Kress M, Lutz B, Woolf CJ, Kuner R. Agarwal N, et al. Nat Neurosci. 2007 Jul;10(7):870-9. doi: 10.1038/nn1916. Epub 2007 Jun 10. Nat Neurosci. 2007. PMID: 17558404 Free PMC article.
2,503 results