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IFN-α and CD46 stimulation are associated with active lupus and skew natural T regulatory cell differentiation to type 1 regulatory T (Tr1) cells.
Le Buanec H, Gougeon ML, Mathian A, Lebon P, Dupont JM, Peltre G, Hemon P, Schmid M, Bizzini B, Künding T, Burny A, Bensussan A, Amoura Z, Gallo RC, Zagury D. Le Buanec H, et al. Among authors: mathian a. Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):18995-9000. doi: 10.1073/pnas.1113301108. Epub 2011 Nov 7. Proc Natl Acad Sci U S A. 2011. PMID: 22065791 Free PMC article.
IFNalpha kinoid vaccine-induced neutralizing antibodies prevent clinical manifestations in a lupus flare murine model.
Zagury D, Le Buanec H, Mathian A, Larcier P, Burnett R, Amoura Z, Emilie D, Peltre G, Bensussan A, Bizzini B, Gallo RC, Koutouzov S. Zagury D, et al. Among authors: mathian a. Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5294-9. doi: 10.1073/pnas.0900615106. Epub 2009 Mar 11. Proc Natl Acad Sci U S A. 2009. PMID: 19279210 Free PMC article.
Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor.
Miyara M, Yoshioka Y, Kitoh A, Shima T, Wing K, Niwa A, Parizot C, Taflin C, Heike T, Valeyre D, Mathian A, Nakahata T, Yamaguchi T, Nomura T, Ono M, Amoura Z, Gorochov G, Sakaguchi S. Miyara M, et al. Among authors: mathian a. Immunity. 2009 Jun 19;30(6):899-911. doi: 10.1016/j.immuni.2009.03.019. Epub 2009 May 21. Immunity. 2009. PMID: 19464196 Free article.
Active immunisation of human interferon α transgenic mice with a human interferon α Kinoid induces antibodies that neutralise interferon α in sera from patients with systemic lupus erythematosus.
Mathian A, Amoura Z, Adam E, Colaone F, Hoekman MF, Dhellin O, Vandepapelière P, Haroche J, Piette JC, Lebon P, Grouard-Vogel G. Mathian A, et al. Ann Rheum Dis. 2011 Jun;70(6):1138-43. doi: 10.1136/ard.2010.141101. Epub 2011 Mar 9. Ann Rheum Dis. 2011. PMID: 21389044
225 results