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Dominance of amyloid precursor protein sequence over host cell secretases in determining beta-amyloid profiles studies of interspecies variation and drug action by internally standardized immunoprecipitation/mass spectrometry.
Du P, Wood KM, Rosner MH, Cunningham D, Tate B, Geoghegan KF. Du P, et al. Among authors: tate b. J Pharmacol Exp Ther. 2007 Mar;320(3):1144-52. doi: 10.1124/jpet.106.114561. Epub 2007 Jan 3. J Pharmacol Exp Ther. 2007. PMID: 17202404
Concentration-dependent modulation of amyloid-beta in vivo and in vitro using the gamma-secretase inhibitor, LY-450139.
Lanz TA, Karmilowicz MJ, Wood KM, Pozdnyakov N, Du P, Piotrowski MA, Brown TM, Nolan CE, Richter KE, Finley JE, Fei Q, Ebbinghaus CF, Chen YL, Spracklin DK, Tate B, Geoghegan KF, Lau LF, Auperin DD, Schachter JB. Lanz TA, et al. Among authors: tate b. J Pharmacol Exp Ther. 2006 Nov;319(2):924-33. doi: 10.1124/jpet.106.110700. Epub 2006 Aug 18. J Pharmacol Exp Ther. 2006. PMID: 16920992
Pharmacodynamics and pharmacokinetics of the gamma-secretase inhibitor PF-3084014.
Lanz TA, Wood KM, Richter KE, Nolan CE, Becker SL, Pozdnyakov N, Martin BA, Du P, Oborski CE, Wood DE, Brown TM, Finley JE, Sokolowski SA, Hicks CD, Coffman KJ, Geoghegan KF, Brodney MA, Liston D, Tate B. Lanz TA, et al. Among authors: tate b. J Pharmacol Exp Ther. 2010 Jul;334(1):269-77. doi: 10.1124/jpet.110.167379. Epub 2010 Apr 2. J Pharmacol Exp Ther. 2010. PMID: 20363853
Molecular and cellular biology of Alzheimer amyloid.
Marotta CA, Majocha RE, Tate B. Marotta CA, et al. Among authors: tate b. J Mol Neurosci. 1992;3(3):111-25. doi: 10.1007/BF02919403. J Mol Neurosci. 1992. PMID: 1627458 Review.
136 results