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Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance.
Gotink KJ, Broxterman HJ, Labots M, de Haas RR, Dekker H, Honeywell RJ, Rudek MA, Beerepoot LV, Musters RJ, Jansen G, Griffioen AW, Assaraf YG, Pili R, Peters GJ, Verheul HM. Gotink KJ, et al. Among authors: griffioen aw. Clin Cancer Res. 2011 Dec 1;17(23):7337-46. doi: 10.1158/1078-0432.CCR-11-1667. Epub 2011 Oct 6. Clin Cancer Res. 2011. PMID: 21980135 Free PMC article.
Signalling pathways in vasculogenic mimicry.
Paulis YW, Soetekouw PM, Verheul HM, Tjan-Heijnen VC, Griffioen AW. Paulis YW, et al. Among authors: griffioen aw. Biochim Biophys Acta. 2010 Aug;1806(1):18-28. doi: 10.1016/j.bbcan.2010.01.001. Epub 2010 Jan 14. Biochim Biophys Acta. 2010. PMID: 20079807 Review.
Tumor cells secrete galectin-1 to enhance endothelial cell activity.
Thijssen VL, Barkan B, Shoji H, Aries IM, Mathieu V, Deltour L, Hackeng TM, Kiss R, Kloog Y, Poirier F, Griffioen AW. Thijssen VL, et al. Among authors: griffioen aw. Cancer Res. 2010 Aug 1;70(15):6216-24. doi: 10.1158/0008-5472.CAN-09-4150. Epub 2010 Jul 20. Cancer Res. 2010. PMID: 20647324
Angiostatic kinase inhibitors to sustain photodynamic angio-occlusion.
Nowak-Sliwinska P, Weiss A, van Beijnum JR, Wong TJ, Ballini JP, Lovisa B, van den Bergh H, Griffioen AW. Nowak-Sliwinska P, et al. Among authors: griffioen aw. J Cell Mol Med. 2012 Jul;16(7):1553-62. doi: 10.1111/j.1582-4934.2011.01440.x. J Cell Mol Med. 2012. PMID: 21880113 Free PMC article.
Acquired tumor cell resistance to sunitinib causes resistance in a HT-29 human colon cancer xenograft mouse model without affecting sunitinib biodistribution or the tumor microvasculature.
Gotink KJ, Broxterman HJ, Honeywell RJ, Dekker H, de Haas RR, Miles KM, Adelaiye R, Griffioen AW, Peters GJ, Pili R, Verheul HM. Gotink KJ, et al. Among authors: griffioen aw. Oncoscience. 2014 Dec 15;1(12):844-53. doi: 10.18632/oncoscience.106. eCollection 2014. Oncoscience. 2014. PMID: 25621299 Free PMC article.
295 results