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A phase 2 randomized trial of ELND005, scyllo-inositol, in mild to moderate Alzheimer disease.
Salloway S, Sperling R, Keren R, Porsteinsson AP, van Dyck CH, Tariot PN, Gilman S, Arnold D, Abushakra S, Hernandez C, Crans G, Liang E, Quinn G, Bairu M, Pastrak A, Cedarbaum JM; ELND005-AD201 Investigators. Salloway S, et al. Among authors: cedarbaum jm. Neurology. 2011 Sep 27;77(13):1253-62. doi: 10.1212/WNL.0b013e3182309fa5. Epub 2011 Sep 14. Neurology. 2011. PMID: 21917766 Free PMC article. Clinical Trial.
Targeting Prodromal Alzheimer Disease With Avagacestat: A Randomized Clinical Trial.
Coric V, Salloway S, van Dyck CH, Dubois B, Andreasen N, Brody M, Curtis C, Soininen H, Thein S, Shiovitz T, Pilcher G, Ferris S, Colby S, Kerselaers W, Dockens R, Soares H, Kaplita S, Luo F, Pachai C, Bracoud L, Mintun M, Grill JD, Marek K, Seibyl J, Cedarbaum JM, Albright C, Feldman HH, Berman RM. Coric V, et al. Among authors: cedarbaum jm. JAMA Neurol. 2015 Nov;72(11):1324-33. doi: 10.1001/jamaneurol.2015.0607. JAMA Neurol. 2015. PMID: 26414022 Clinical Trial.
Pharmacokinetic Profile of Orally Administered Scyllo-Inositol (Elnd005) in Plasma, Cerebrospinal Fluid and Brain, and Corresponding Effect on Amyloid-Beta in Healthy Subjects.
Liang E, Garzone P, Cedarbaum JM, Koller M, Tran T, Xu V, Ross B, Jhee SS, Ereshefsky L, Pastrak A, Abushakra S. Liang E, et al. Among authors: cedarbaum jm. Clin Pharmacol Drug Dev. 2013 Apr;2(2):186-94. doi: 10.1002/cpdd.14. Epub 2013 Mar 16. Clin Pharmacol Drug Dev. 2013. PMID: 27121673
Disease modification and biomarker development in Parkinson disease: Revision or reconstruction?
Espay AJ, Kalia LV, Gan-Or Z, Williams-Gray CH, Bedard PL, Rowe SM, Morgante F, Fasano A, Stecher B, Kauffman MA, Farrer MJ, Coffey CS, Schwarzschild MA, Sherer T, Postuma RB, Strafella AP, Singleton AB, Barker RA, Kieburtz K, Olanow CW, Lozano A, Kordower JH, Cedarbaum JM, Brundin P, Standaert DG, Lang AE. Espay AJ, et al. Among authors: cedarbaum jm. Neurology. 2020 Mar 17;94(11):481-494. doi: 10.1212/WNL.0000000000009107. Epub 2020 Feb 26. Neurology. 2020. PMID: 32102975 Free PMC article. Review.
151 results