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B-cell depletion in vitro and in vivo with an afucosylated anti-CD19 antibody.
Herbst R, Wang Y, Gallagher S, Mittereder N, Kuta E, Damschroder M, Woods R, Rowe DC, Cheng L, Cook K, Evans K, Sims GP, Pfarr DS, Bowen MA, Dall'Acqua W, Shlomchik M, Tedder TF, Kiener P, Jallal B, Wu H, Coyle AJ. Herbst R, et al. Among authors: coyle aj. J Pharmacol Exp Ther. 2010 Oct;335(1):213-22. doi: 10.1124/jpet.110.168062. Epub 2010 Jul 6. J Pharmacol Exp Ther. 2010. PMID: 20605905
MEDI-563, a humanized anti-IL-5 receptor alpha mAb with enhanced antibody-dependent cell-mediated cytotoxicity function.
Kolbeck R, Kozhich A, Koike M, Peng L, Andersson CK, Damschroder MM, Reed JL, Woods R, Dall'acqua WW, Stephens GL, Erjefalt JS, Bjermer L, Humbles AA, Gossage D, Wu H, Kiener PA, Spitalny GL, Mackay CR, Molfino NA, Coyle AJ. Kolbeck R, et al. Among authors: coyle aj. J Allergy Clin Immunol. 2010 Jun;125(6):1344-1353.e2. doi: 10.1016/j.jaci.2010.04.004. J Allergy Clin Immunol. 2010. PMID: 20513525
Genomic-based high throughput screening identifies small molecules that differentially inhibit the antiviral and immunomodulatory effects of IFN-alpha.
Chen B, Zong Q, Cibotti R, Morris C, Castaneda J, Naiman B, Liu D, Glodek A, Sims GP, Herbst R, Horrigan SK, Kiener PA, Soppet D, Coyle AJ, Audoly L. Chen B, et al. Among authors: coyle aj. Mol Med. 2008 Jul-Aug;14(7-8):374-82. doi: 10.2119/2008-00028.Chen. Mol Med. 2008. PMID: 18475307 Free PMC article.
Neutralization of interferon-alpha/beta-inducible genes and downstream effect in a phase I trial of an anti-interferon-alpha monoclonal antibody in systemic lupus erythematosus.
Yao Y, Richman L, Higgs BW, Morehouse CA, de los Reyes M, Brohawn P, Zhang J, White B, Coyle AJ, Kiener PA, Jallal B. Yao Y, et al. Among authors: coyle aj. Arthritis Rheum. 2009 Jun;60(6):1785-96. doi: 10.1002/art.24557. Arthritis Rheum. 2009. PMID: 19479852 Free article. Clinical Trial.
HMGB1 and RAGE in inflammation and cancer.
Sims GP, Rowe DC, Rietdijk ST, Herbst R, Coyle AJ. Sims GP, et al. Among authors: coyle aj. Annu Rev Immunol. 2010;28:367-88. doi: 10.1146/annurev.immunol.021908.132603. Annu Rev Immunol. 2010. PMID: 20192808 Review.
Type I interferon: potential therapeutic target for psoriasis?
Yao Y, Richman L, Morehouse C, de los Reyes M, Higgs BW, Boutrin A, White B, Coyle A, Krueger J, Kiener PA, Jallal B. Yao Y, et al. PLoS One. 2008 Jul 16;3(7):e2737. doi: 10.1371/journal.pone.0002737. PLoS One. 2008. PMID: 18648529 Free PMC article.
Opposing roles of membrane and soluble forms of the receptor for advanced glycation end products in primary respiratory syncytial virus infection.
Miller AL, Sims GP, Brewah YA, Rebelatto MC, Kearley J, Benjamin E, Keller AE, Brohawn P, Herbst R, Coyle AJ, Humbles AA, Kolbeck R. Miller AL, et al. Among authors: coyle aj. J Infect Dis. 2012 Apr 15;205(8):1311-20. doi: 10.1093/infdis/jir826. Epub 2012 Jan 18. J Infect Dis. 2012. PMID: 22262795 Free PMC article.
213 results