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Design and synthesis of 1,3-biarylsulfanyl derivatives as new anti-breast cancer agents.
Kumar A, Tripathi VD, Kumar P, Gupta LP, Akanksha, Trivedi R, Bid H, Nayak VL, Siddiqui JA, Chakravarti B, Saxena R, Dwivedi A, Siddiquee MI, Siddiqui U, Konwar R, Chattopadhyay N. Kumar A, et al. Among authors: saxena r. Bioorg Med Chem. 2011 Sep 15;19(18):5409-19. doi: 10.1016/j.bmc.2011.07.056. Epub 2011 Aug 2. Bioorg Med Chem. 2011. PMID: 21871812
Corrigendum to "Design and synthesis of 1,3-biarylsulfanyl derivatives as new anti-breast cancer agents" [Bioorg. Med. Chem. 19 (2011) 5409-5419].
Kumar A, Tripathi VD, Kumar P, Gupta LP, Akanksha, Trivedi R, Bid H, Nayak VL, Siddiqui JA, Chakravarti B, Saxena R, Dwivedi A, Siddiquee MI, Siddiqui U, Konwar R, Chattopadhyay N. Kumar A, et al. Among authors: saxena r. Bioorg Med Chem. 2019 Sep 1;27(17):3960-3961. doi: 10.1016/j.bmc.2019.07.018. Epub 2019 Jul 22. Bioorg Med Chem. 2019. PMID: 31345744 No abstract available.
Chemotherapeutic Potential of 2-[Piperidinoethoxyphenyl]-3-Phenyl-2H-Benzo(b)pyran in Estrogen Receptor- Negative Breast Cancer Cells: Action via Prevention of EGFR Activation and Combined Inhibition of PI-3-K/Akt/FOXO and MEK/Erk/AP-1 Pathways.
Saxena R, Chandra V, Manohar M, Hajela K, Debnath U, Prabhakar YS, Saini KS, Konwar R, Kumar S, Megu K, Roy BG, Dwivedi A. Saxena R, et al. PLoS One. 2013 Jun 19;8(6):e66246. doi: 10.1371/journal.pone.0066246. Print 2013. PLoS One. 2013. PMID: 23840429 Free PMC article. Retracted.
Spiro-oxindole derivative 5-chloro-4',5'-diphenyl-3'-(4-(2-(piperidin-1-yl) ethoxy) benzoyl) spiro[indoline-3,2'-pyrrolidin]-2-one triggers apoptosis in breast cancer cells via restoration of p53 function.
Saxena R, Gupta G, Manohar M, Debnath U, Popli P, Prabhakar YS, Konwar R, Kumar S, Kumar A, Dwivedi A. Saxena R, et al. Int J Biochem Cell Biol. 2016 Jan;70:105-17. doi: 10.1016/j.biocel.2015.11.003. Epub 2015 Nov 7. Int J Biochem Cell Biol. 2016. PMID: 26556313
Benzopyran derivative CDRI-85/287 induces G2-M arrest in estrogen receptor-positive breast cancer cells via modulation of estrogen receptors α- and β-mediated signaling, in parallel to EGFR signaling and suppresses the growth of tumor xenograft.
Saxena R, Fatima I, Chandra V, Blesson CS, Kharkwal G, Hussain MK, Hajela K, Roy BG, Dwivedi A. Saxena R, et al. Steroids. 2013 Nov;78(11):1071-86. doi: 10.1016/j.steroids.2013.07.004. Epub 2013 Jul 26. Steroids. 2013. PMID: 23891847
2,3-Diaryl-2H-1-benzopyran derivatives interfere with classical and non-classical estrogen receptor signaling pathways, inhibit Akt activation and induce apoptosis in human endometrial cancer cells.
Fatima I, Chandra V, Saxena R, Manohar M, Sanghani Y, Hajela K, Negi MP, Sankhwar PL, Jain SK, Dwivedi A. Fatima I, et al. Among authors: saxena r. Mol Cell Endocrinol. 2012 Jan 2;348(1):198-210. doi: 10.1016/j.mce.2011.08.018. Epub 2011 Aug 22. Mol Cell Endocrinol. 2012. PMID: 21878365
The anti-proliferative effect of 2-[piperidinoethoxyphenyl]-3-[4-hydroxyphenyl]-2H-benzo(b) pyran is potentiated via induction of estrogen receptor beta and p21 in human endometrial adenocarcinoma cells.
Fatima I, Saxena R, Kharkwal G, Hussain MK, Yadav N, Hajela K, Sankhwar PL, Dwivedi A. Fatima I, et al. Among authors: saxena r. J Steroid Biochem Mol Biol. 2013 Nov;138:123-31. doi: 10.1016/j.jsbmb.2013.04.005. Epub 2013 May 18. J Steroid Biochem Mol Biol. 2013. PMID: 23688837
2,488 results