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SIRT1-mediated acute cardioprotection.
Nadtochiy SM, Yao H, McBurney MW, Gu W, Guarente L, Rahman I, Brookes PS. Nadtochiy SM, et al. Among authors: gu w. Am J Physiol Heart Circ Physiol. 2011 Oct;301(4):H1506-12. doi: 10.1152/ajpheart.00587.2011. Epub 2011 Aug 19. Am J Physiol Heart Circ Physiol. 2011. PMID: 21856913 Free PMC article.
Mammalian SIRT1 represses forkhead transcription factors.
Motta MC, Divecha N, Lemieux M, Kamel C, Chen D, Gu W, Bultsma Y, McBurney M, Guarente L. Motta MC, et al. Among authors: gu w. Cell. 2004 Feb 20;116(4):551-63. doi: 10.1016/s0092-8674(04)00126-6. Cell. 2004. PMID: 14980222 Free article.
SIRT1 transgenic mice show phenotypes resembling calorie restriction.
Bordone L, Cohen D, Robinson A, Motta MC, van Veen E, Czopik A, Steele AD, Crowe H, Marmor S, Luo J, Gu W, Guarente L. Bordone L, et al. Among authors: gu w. Aging Cell. 2007 Dec;6(6):759-67. doi: 10.1111/j.1474-9726.2007.00335.x. Epub 2007 Sep 17. Aging Cell. 2007. PMID: 17877786 Free article.
SIRT1 redresses the imbalance of tissue inhibitor of matrix metalloproteinase-1 and matrix metalloproteinase-9 in the development of mouse emphysema and human COPD.
Yao H, Hwang JW, Sundar IK, Friedman AE, McBurney MW, Guarente L, Gu W, Kinnula VL, Rahman I. Yao H, et al. Among authors: gu w. Am J Physiol Lung Cell Mol Physiol. 2013 Nov 1;305(9):L615-24. doi: 10.1152/ajplung.00249.2012. Epub 2013 Sep 13. Am J Physiol Lung Cell Mol Physiol. 2013. PMID: 24039251 Free PMC article.
Negative regulation of the deacetylase SIRT1 by DBC1.
Zhao W, Kruse JP, Tang Y, Jung SY, Qin J, Gu W. Zhao W, et al. Among authors: gu w. Nature. 2008 Jan 31;451(7178):587-90. doi: 10.1038/nature06515. Nature. 2008. PMID: 18235502 Free PMC article.
How does SIRT1 affect metabolism, senescence and cancer?
Brooks CL, Gu W. Brooks CL, et al. Among authors: gu w. Nat Rev Cancer. 2009 Feb;9(2):123-8. doi: 10.1038/nrc2562. Epub 2008 Dec 29. Nat Rev Cancer. 2009. PMID: 19132007 Free PMC article. Review.
5,754 results