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Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency.
Nat Commun. 2020 Feb 14;11(1):910. doi: 10.1038/s41467-020-14638-w.
Nat Commun. 2020.
PMID: 32060399
Free PMC article.
TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function.
Gómez-Herreros F, Schuurs-Hoeijmakers JH, McCormack M, Greally MT, Rulten S, Romero-Granados R, Counihan TJ, Chaila E, Conroy J, Ennis S, Delanty N, Cortés-Ledesma F, de Brouwer AP, Cavalleri GL, El-Khamisy SF, de Vries BB, Caldecott KW.
Gómez-Herreros F, et al. Among authors: romero granados r.
Nat Genet. 2014 May;46(5):516-21. doi: 10.1038/ng.2929. Epub 2014 Mar 23.
Nat Genet. 2014.
PMID: 24658003
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TDP2-dependent non-homologous end-joining protects against topoisomerase II-induced DNA breaks and genome instability in cells and in vivo.
Gómez-Herreros F, Romero-Granados R, Zeng Z, Alvarez-Quilón A, Quintero C, Ju L, Umans L, Vermeire L, Huylebroeck D, Caldecott KW, Cortés-Ledesma F.
Gómez-Herreros F, et al. Among authors: romero granados r.
PLoS Genet. 2013;9(3):e1003226. doi: 10.1371/journal.pgen.1003226. Epub 2013 Mar 7.
PLoS Genet. 2013.
PMID: 23505375
Free PMC article.
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Postnatal proteasome inhibition induces neurodegeneration and cognitive deficiencies in adult mice: a new model of neurodevelopment syndrome.
Romero-Granados R, Fontán-Lozano Á, Aguilar-Montilla FJ, Carrión ÁM.
Romero-Granados R, et al.
PLoS One. 2011;6(12):e28927. doi: 10.1371/journal.pone.0028927. Epub 2011 Dec 12.
PLoS One. 2011.
PMID: 22174927
Free PMC article.
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The kreisler mutation leads to the loss of intrinsically hypoxia-activated spots in the region of the retrotrapezoid nucleus/parafacial respiratory group.
Voituron N, Frugière A, Mc Kay LC, Romero-Granados R, Domínguez-Del-Toro E, Saadani-Makki F, Champagnat J, Bodineau L.
Voituron N, et al. Among authors: romero granados r.
Neuroscience. 2011 Oct 27;194:95-111. doi: 10.1016/j.neuroscience.2011.07.062. Epub 2011 Jul 31.
Neuroscience. 2011.
PMID: 21839147
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From learning to forgetting: behavioral, circuitry, and molecular properties define the different functional states of the recognition memory trace.
Romero-Granados R, Fontán-Lozano A, Delgado-García JM, Carrión AM.
Romero-Granados R, et al.
Hippocampus. 2010 May;20(5):584-95. doi: 10.1002/hipo.20669.
Hippocampus. 2010.
PMID: 19603520
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Lack of DREAM protein enhances learning and memory and slows brain aging.
Fontán-Lozano A, Romero-Granados R, del-Pozo-Martín Y, Suárez-Pereira I, Delgado-García JM, Penninger JM, Carrión AM.
Fontán-Lozano A, et al. Among authors: romero granados r.
Curr Biol. 2009 Jan 13;19(1):54-60. doi: 10.1016/j.cub.2008.11.056. Epub 2008 Dec 24.
Curr Biol. 2009.
PMID: 19110430
Free article.
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Histone deacetylase inhibitors improve learning consolidation in young and in KA-induced-neurodegeneration and SAMP-8-mutant mice.
Fontán-Lozano A, Romero-Granados R, Troncoso J, Múnera A, Delgado-García JM, Carrión AM.
Fontán-Lozano A, et al. Among authors: romero granados r.
Mol Cell Neurosci. 2008 Oct;39(2):193-201. doi: 10.1016/j.mcn.2008.06.009. Epub 2008 Jun 25.
Mol Cell Neurosci. 2008.
PMID: 18638560
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