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Methotrexate induces intestinal mucositis and alters gut protein metabolism independently of reduced food intake.
Boukhettala N, Leblond J, Claeyssens S, Faure M, Le Pessot F, Bôle-Feysot C, Hassan A, Mettraux C, Vuichoud J, Lavoinne A, Breuillé D, Déchelotte P, Coëffier M. Boukhettala N, et al. Am J Physiol Endocrinol Metab. 2009 Jan;296(1):E182-90. doi: 10.1152/ajpendo.90459.2008. Epub 2008 Nov 4. Am J Physiol Endocrinol Metab. 2009. PMID: 18984853 Free article.
Methotrexate modulates tight junctions through NF-κB, MEK, and JNK pathways.
Beutheu Youmba S, Belmonte L, Galas L, Boukhettala N, Bôle-Feysot C, Déchelotte P, Coëffier M. Beutheu Youmba S, et al. Among authors: boukhettala n. J Pediatr Gastroenterol Nutr. 2012 Apr;54(4):463-70. doi: 10.1097/MPG.0b013e318247240d. J Pediatr Gastroenterol Nutr. 2012. PMID: 22197938
Increased proteasome-mediated degradation of occludin in irritable bowel syndrome.
Coëffier M, Gloro R, Boukhettala N, Aziz M, Lecleire S, Vandaele N, Antonietti M, Savoye G, Bôle-Feysot C, Déchelotte P, Reimund JM, Ducrotté P. Coëffier M, et al. Among authors: boukhettala n. Am J Gastroenterol. 2010 May;105(5):1181-8. doi: 10.1038/ajg.2009.700. Epub 2009 Dec 8. Am J Gastroenterol. 2010. PMID: 19997094
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