Fairclough RJ - Search Results

1

Daily treatment with SMTC1100, a novel small molecule utrophin upregulator, dramatically reduces the dystrophic symptoms in the mdx mouse.

Tinsley JM, Fairclough RJ, Storer R, Wilkes FJ, Potter AC, Squire SE, Powell DS, Cozzoli A, Capogrosso RF, Lambert A, Wilson FX, Wren SP, De Luca A, Davies KE. Tinsley JM, et al. Among authors: fairclough rj. PLoS One. 2011 May 6;6(5):e19189. doi: 10.1371/journal.pone.0019189. PLoS One. 2011. PMID: 21573153 Free PMC article.

2

Discovery and mechanism of action studies of 4,6-diphenylpyrimidine-2-carbohydrazides as utrophin modulators for the treatment of Duchenne muscular dystrophy.

Vuorinen A, Wilkinson IVL, Chatzopoulou M, Edwards B, Squire SE, Fairclough RJ, Bazan NA, Milner JA, Conole D, Donald JR, Shah N, Willis NJ, Martínez RF, Wilson FX, Wynne GM, Davies SG, Davies KE, Russell AJ. Vuorinen A, et al. Among authors: fairclough rj. Eur J Med Chem. 2021 Aug 5;220:113431. doi: 10.1016/j.ejmech.2021.113431. Epub 2021 Apr 20. Eur J Med Chem. 2021. PMID: 33915371

3

Progress in therapy for Duchenne muscular dystrophy.

Fairclough RJ, Bareja A, Davies KE. Fairclough RJ, et al. Exp Physiol. 2011 Nov;96(11):1101-13. doi: 10.1113/expphysiol.2010.053025. Epub 2011 Jul 31. Exp Physiol. 2011. PMID: 21804140 Free article. Review.

4

Pharmacologically targeting the primary defect and downstream pathology in Duchenne muscular dystrophy.

Fairclough RJ, Perkins KJ, Davies KE. Fairclough RJ, et al. Curr Gene Ther. 2012 Jun;12(3):206-44. doi: 10.2174/156652312800840595. Curr Gene Ther. 2012. PMID: 22571500 Review.

5

Therapy for Duchenne muscular dystrophy: renewed optimism from genetic approaches.

Fairclough RJ, Wood MJ, Davies KE. Fairclough RJ, et al. Nat Rev Genet. 2013 Jun;14(6):373-8. doi: 10.1038/nrg3460. Epub 2013 Apr 23. Nat Rev Genet. 2013. PMID: 23609411 Review.

6

Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin.

Li D, Bareja A, Judge L, Yue Y, Lai Y, Fairclough R, Davies KE, Chamberlain JS, Duan D. Li D, et al. J Cell Sci. 2010 Jun 15;123(Pt 12):2008-13. doi: 10.1242/jcs.064808. Epub 2010 May 18. J Cell Sci. 2010. PMID: 20483958 Free PMC article.

7

Hailey-Hailey disease: molecular and clinical characterization of novel mutations in the ATP2C1 gene.

Dobson-Stone C, Fairclough R, Dunne E, Brown J, Dissanayake M, Munro CS, Strachan T, Burge S, Sudbrak R, Monaco AP, Hovnanian A. Dobson-Stone C, et al. J Invest Dermatol. 2002 Feb;118(2):338-43. doi: 10.1046/j.0022-202x.2001.01675.x. J Invest Dermatol. 2002. PMID: 11841554 Free article.

8

Hailey-Hailey disease: identification of novel mutations in ATP2C1 and effect of missense mutation A528P on protein expression levels.

Fairclough RJ, Lonie L, Van Baelen K, Haftek M, Munro CS, Burge SM, Hovnanian A. Fairclough RJ, et al. J Invest Dermatol. 2004 Jul;123(1):67-71. doi: 10.1111/j.0022-202X.2004.22713.x. J Invest Dermatol. 2004. PMID: 15191544 Free article.

9

Calcium pumps and keratinocytes: lessons from Darier's disease and Hailey-Hailey disease.

Dhitavat J, Fairclough RJ, Hovnanian A, Burge SM. Dhitavat J, et al. Among authors: fairclough rj. Br J Dermatol. 2004 May;150(5):821-8. doi: 10.1111/j.1365-2133.2004.05904.x. Br J Dermatol. 2004. PMID: 15149492 Review.

10

Effect of Hailey-Hailey Disease mutations on the function of a new variant of human secretory pathway Ca2+/Mn2+-ATPase (hSPCA1).

Fairclough RJ, Dode L, Vanoevelen J, Andersen JP, Missiaen L, Raeymaekers L, Wuytack F, Hovnanian A. Fairclough RJ, et al. J Biol Chem. 2003 Jul 4;278(27):24721-30. doi: 10.1074/jbc.M300509200. Epub 2003 Apr 21. J Biol Chem. 2003. PMID: 12707275 Free article.

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