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Conformational control inhibition of the BCR-ABL1 tyrosine kinase, including the gatekeeper T315I mutant, by the switch-control inhibitor DCC-2036.
Chan WW, Wise SC, Kaufman MD, Ahn YM, Ensinger CL, Haack T, Hood MM, Jones J, Lord JW, Lu WP, Miller D, Patt WC, Smith BD, Petillo PA, Rutkoski TJ, Telikepalli H, Vogeti L, Yao T, Chun L, Clark R, Evangelista P, Gavrilescu LC, Lazarides K, Zaleskas VM, Stewart LJ, Van Etten RA, Flynn DL. Chan WW, et al. Among authors: clark r. Cancer Cell. 2011 Apr 12;19(4):556-68. doi: 10.1016/j.ccr.2011.03.003. Cancer Cell. 2011. PMID: 21481795 Free PMC article.
Switch control pocket inhibitors of p38-MAP kinase. Durable type II inhibitors that do not require binding into the canonical ATP hinge region.
Ahn YM, Clare M, Ensinger CL, Hood MM, Lord JW, Lu WP, Miller DF, Patt WC, Smith BD, Vogeti L, Kaufman MD, Petillo PA, Wise SC, Abendroth J, Chun L, Clark R, Feese M, Kim H, Stewart L, Flynn DL. Ahn YM, et al. Among authors: clark r. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5793-8. doi: 10.1016/j.bmcl.2010.07.134. Epub 2010 Aug 3. Bioorg Med Chem Lett. 2010. PMID: 20800479
Brain health in diverse settings: How age, demographics and cognition shape brain function.
Hernandez H, Baez S, Medel V, Moguilner S, Cuadros J, Santamaria-Garcia H, Tagliazucchi E, Valdes-Sosa PA, Lopera F, OchoaGómez JF, González-Hernández A, Bonilla-Santos J, Gonzalez-Montealegre RA, Aktürk T, Yıldırım E, Anghinah R, Legaz A, Fittipaldi S, Yener GG, Escudero J, Babiloni C, Lopez S, Whelan R, Lucas AAF, García AM, Huepe D, Caterina GD, Soto-Añari M, Birba A, Sainz-Ballesteros A, Coronel C, Herrera E, Abasolo D, Kilborn K, Rubido N, Clark R, Herzog R, Yerlikaya D, Güntekin B, Parra MA, Prado P, Ibanez A. Hernandez H, et al. Among authors: clark r. Neuroimage. 2024 May 21;295:120636. doi: 10.1016/j.neuroimage.2024.120636. Online ahead of print. Neuroimage. 2024. PMID: 38777219 Free article.
7,261 results